Spontaneous Bacterial Peritonitis Caused byHafnia alveiin a Patient with Liver Cirrhosis

Abstract

Hafnia alvei is a gram-negative bacillus that is rarely isolated from human clinical specimens and is rarely pathogenic. This organism is an extremely uncommon cause of spontaneous bacterial peritonitis (SBP). We report a case of an 83-year-old male with hepatitis C-associated liver cirrhosis and hepatocellular carcinoma who was diagnosed with SBP caused by H. alvei. He was admitted to an university-affiliated hospital with fever and abdominal pain. There were 2 episodes of SBP during 2 months. Although isolates of H. alvei from ascitic fluid were shown to be susceptible to cefotaxime, responses for cefotaxime treatment were inadequate in both episodes. Therefore, cefotaxime was switched to imipenem in the first episode and to ciprofloxacin in the second, according to the results of antimicrobial susceptibility.After the antibiotics was changed, SBP was resolved.

"Hafnia alvei Urinary Tract Infection in A Patient with Multimorbidity After Covid19 - A Case Report"

“…In earlier studies, its connection to the clinical infection is debated [5] but after 2000, there is an increasing number of case reports in which Hafnia alvei is involved in human infections. For example, Hafnia alvei is reported to cause complicated [6][7][8][9] and uncomplicated UTIs [11], bacteremia and sepsis [12][13][14][15][16][17][18][19][20][21][22][23], hemolytic uremic syndrome [24], peritonitis [25,26], chorioamnionitis and preterm birth [27], deep infection in open fractures [28],…”

The pathogenHafnia alveiin veterinary medicine: a review

“…As pathogen, humans have generally been considered an opportunistic bacteria, and may cause infections associated to underlying illnesses or predisposing factors as immunocompromised patients (Sakazaki & Tamura 1992), causing septicaemia (Englund 1969;Ginsberg & Goldsmith 1988;Fazal et al 1997;Liu et al 2007), endocarditis (Gallego et al 1999;Loulergue et al 2007), meningitis (Mojtabaee & Siadati 1978), pneumonia (Klapholz et al 1994;Fazal et al 1997), abscesses (Agustin & Cunha 1995), urinary infections (Sakazaki & Tamura 1992;Krieg & Sneath 1994;Ramos & Dámaso 2000;Cardile et al 2011), peritonitis (Jung et al 2010;Yap et al 2010), endophthalmitis (Ruiz-Moreno et al 2001), cholecystitis (Palaniswamy et al 2009), intestinal disorders (Harada et al 1957;Emslie-Smith 1961;Ratnam 1991;Westblom & Milligan 1992;Reina et al 1993;Ridell et al 1994) and postenteritic arthritis (Newmark et al 1994).…”