2015
DOI: 10.1111/cup.12595
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Spongiotic dermatitis with Langerhans cell microvesicles

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“…[10][11][12] Notably, LCs seem to play a direct role in the intraepidermal vesiculation seen in spongiotic dermatitis. 13 In eradicating HPV skin infection, LCs act particularly through toll-like receptor (TLR)-3-induced production of interferon (IFN)-inducible chemokines, which augments the T-cell-mediated response. [14][15][16] Lack of LCs may hinder the cell-mediated inflammatory response to HPV infection, preventing wart regression.…”
Section: Discussionmentioning
confidence: 99%
“…[10][11][12] Notably, LCs seem to play a direct role in the intraepidermal vesiculation seen in spongiotic dermatitis. 13 In eradicating HPV skin infection, LCs act particularly through toll-like receptor (TLR)-3-induced production of interferon (IFN)-inducible chemokines, which augments the T-cell-mediated response. [14][15][16] Lack of LCs may hinder the cell-mediated inflammatory response to HPV infection, preventing wart regression.…”
Section: Discussionmentioning
confidence: 99%