Spondylodiscitis representing as the very first sign of Crohnʼs disease

“…In fact, in these studies, based on the ESSG SpA criteria [17], the authors have detected a prevalence between 10% and 25% of spondylitis, and between 30% and 36% of sacroiliitis [20, 22, 23]. A complication of the axial subset in patients with IBD is the development of sclerotic erosive lesions in the adjacent vertebral bodies [74] or aseptic spondylodiscitis, also defined as Andersson lesions (ALs) [75], whose diagnosis is often delayed, particularly in patients having an insidious onset and nonspecific symptoms [76]. Our research group has recently investigated the occurrence and the clinical features of ALs arthritis in EA, detected by magnetic resonance imaging, an imaging technique usually accepted to evaluate the axial and peripheral involvement of SpA [77–79], and we found an high prevalence of this lesion among EA patients (30.55%), confirming that ALs are an important characteristic aspect of SpA.…”

Section: Pathogenesismentioning

confidence: 99%

Enteropathic Spondyloarthritis: From Diagnosis to Treatment

Peluso

Minno

Iervolino

et al. 2013

Clinical and Developmental Immunology

View full text Add to dashboard Cite

Enteropathic arthritis (EA) is a spondyloarthritis (SpA) which occurs in patients with inflammatory bowel diseases (IBDs) and other gastrointestinal diseases. Diagnosis is generally established on the medical history and physical examination. It was, generally, made according to the European Spondyloarthropathy Study Group (ESSG) criteria. Rheumatic manifestations are the most frequent extraintestinal findings of IBD with a prevalence between 17% and 39%, and IBD is associated, less frequently, with other rheumatic disease such as rheumatoid arthritis, Sjogren syndrome, Takayasu arteritis, and fibromyalgia. Although the pathogenesis of EA has not been plainly clarified, the most popular theory supposes that joint inflammation occurs in genetically predisposed subjects with bacterial gut infections, provided an important evidence for a possible relationship between inflammation of the gut mucosa and arthritis. The management of patients with EA requires an active cooperation between the gastroenterologist and rheumatologist.

show abstract