Abstract-In this paper, the uniaxial anisotropic perfectly matched layer (UPML) absorbing boundary condition in unconditionally stable five-step locally one-dimensional finite-difference time-domain (LOD5-FDTD) method is deduced. The UPML absorbing boundary condition (ABC) is validated based on comparison with a simulation in larger domain (and thus without reflection) in the first test. Then using a sinusoidal source, target field phase distribution surrounded by the UPML-ABC is analyzed. The results further illustrate the stability and efficiency of the UPML absorbing boundary condition.