Split-dose <i>vs</i> same-day bowel preparation for afternoon colonoscopies: A meta-analysis of randomized controlled trials

Parsa, Nasim; Grisham, Eric; Cockerell, C. J.; Matteson-Kome, Michelle L.; Bysani, Ramakrishna V; Samiullah, Sami; Nguyen, Douglas L.; Tahan, Veysel; Ghouri, Yezaz A.; Puli, Srinivas R.; Bechtold, Matthew L.

doi:10.13105/wjma.v8.i6.462

Cited by 1 publication

(1 citation statement)

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“…Numerous studies (Matro et al, 2010;Parsa et al, 2020) have shown an increased risk of adverse effects, such as nausea and vomiting, when PEG is administered in split doses. The present investigation was unable to identify any substantial variations in the incidence of adverse effects between the two groups.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of single-versus split-dose polyethylene glycol for colonic preparation

Khan¹,

Haider²,

Latif

et al. 2023

ijhs

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Background: Before a colonoscopy, polyethylene glycol (PEG) is often used to prepare the colon. PEG dosage recommendations are still up for discussion. In this randomized controlled experiment, the effectiveness and acceptability of PEG administered in single vs. split doses for colonic preparation was compared. Methods: A total of 120 individuals were randomized to either split-dose PEG for colonic preparation or a single-dose PEG at Department of Gastroenterology, Hayatabad medical complex. The Boston Bowel Preparation Scale (BBPS) was used for assessing the rate of bowel cleaning for the colonoscopy. A visual analog scale was used to evaluate the preparation's acceptability and tolerability. Results: The quality of colonic preparation was considerably greater in the split-dose PEG group than in the single-dose PEG group, as shown by the BBPS score, which was significantly higher in the split-dose PEG group (7.5±1.2) than in the single-dose PEG group (6.3±1.3) (P0.001). Patient satisfaction did not vary significantly between the two groups, but the split-dose PEG group had a higher completion rate of colonoscopies (97% vs. 95%) as well as greater patient acceptability and tolerance.

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Section: Discussionmentioning

confidence: 99%