Splenic Protective Effect of White Turmeric Extract Against Copper Toxicity in Male Wistar Rats

Chiuman, Linda

doi:10.22159/ajpcr.2021.v14i5.40789

Cited by 2 publications

(3 citation statements)

References 11 publications

(11 reference statements)

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“…The dragon fruit peel extract was formulated into an oral suspension made of Na-CMC. 400 mg dragon fruit peels methanol extract and 20 mg loperamide were mixed into 10 ml 0.5% Na-CMC to form dragon fruit peels methanol extract and standard, respectively (Kanon, Fatimawati and Bodhi, 2012;Chiuman, 2019;Mutia and Chiuman, 2019).…”

Section: Oral Suspension Formulationmentioning

confidence: 99%

In Vitro and In Vivo Antidiarrheal Activity of Dragon Fruit Peels Methanolic Extract

Yosefa,

Tandanu,

Leslie

et al. 2023

Trad.Med.J

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Diarrhea is a global major health problem reported by 2.5 billion cases annually. Diarrhea accounts for 9% of child death worldwide or the second leading cause of death among toddlers. Many local people have used traditional medicine for diarrhea therapy. Dragon fruit is a herbal plant with high vitamins and various nutritious compounds. Therefore, this study determined antidiarrheal activity from dragon fruit peel methanolic extract (Hylocereus polyrhizus). This study was experimental with in vitro and in vivo models. The in vitro model used disc diffusion and microdilution assay against the diarrhea-causing pathogen (Escherichia coli). Meanwhile, the in vivo model used male Wistar rats induced by Castro oil. This study showed that the minimum inhibitory concentration (MIC) and minimum killing concentration (MKC) of dragon fruit peel extract against Escherichia coli were 50 and 100 mg/ml, respectively. The increased dose of dragon fruit peel methanol extract has increased the antidiarrheal index. The highest and lowest antidiarrheal index was found in the dragon fruit methanol extract-3 (76.56%) and dragon fruit methanol extract-1 (43.28%). The dragon fruit peel methanol extract can be proposed as antidiarrhea and antibacterial therapy against the diarrhea-causing pathogen.

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Section: Oral Suspension Formulationmentioning

confidence: 99%

In Vitro and In Vivo Antidiarrheal Activity of Dragon Fruit Peels Methanolic Extract

Yosefa,

Tandanu,

Leslie

et al. 2023

Trad.Med.J

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“…Solanum torvum Swartz is a wild plant species of the solanaceae family which produces berries referred to as turkey berries or wild eggplant. This solanaceae is essential plant in many tropical areas of the world as Africa and West Indies [1,2], Malaysia, China and Philippine [3], Thailand [4], where it constitutes a traditional vegetable and a great tool in traditional medicine for the natives. Although growing spontaneously on moist and fertile soils, S torvum is nowadays cultivated in Africa and the West Indies [5].…”

Section: Introductionmentioning

confidence: 99%

“…It is also cultivated as a small-scale vegetable in southern and eastern Asia, and is especially popular in Thailand [4]. In terms of traditional medicine, the berries of S. torvum have been widely investigated in many countries [2,6,7,8,9,10,11]. Extracts from these berries have generally been shown to be antioxidants, antimicrobials, anti-inflammatories, cardioprotectors, nephroprotectors, hepatoprotectors and cough suppressants.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant Activities, Phenolic Compounds and Organic Acids of Raw and Boiled Berries of Solanum Torvum Swartz From Eastern Côte d’Ivoire

Kouadio,

Adingra

et al. 2022

IFSTJ

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Berries of solanum torvum, referred to as wild eggplant, are widely consumed in eastern Côte d'Ivoire in boiled form in sauces or soups. This study aimed to evaluate the antioxidant potential of these fruits through the estimation of antioxidant capacities of the extracts, identification and quantification of phenolic compounds and organic acids of raw berries and boiled berries to gauge the influence of this cooking. Results showed that boiling caused a considerable decrease in the antioxidant capacity of S. torvum berry extracts. By DPPH scavenging, the effective concentration (EC50) value of extract increased from 20.00 to 42.20 µg/mL, respectively for raw and boiled berries. Regarding EC50 values for antioxidant activities via FRAP, the values of 75.10 and 87.20 µg/mL were obtained, respectively for raw and boiled berries extract. In terms of phenolic compounds, the most predominant were catechin and gallic acid with respective contents of 1.06 and 0.86 mg/kg in the raw berries; 0.86 and 0.71 mg/kg in boiled berries, demonstrating the decrease in levels of these compounds by boiling. Organic acids showed the same decreasing trend during boiling. However, using cooking water when preparing soups or sauces could minimize these losses. In addition to this, one could consider other cooking methods such as steaming to better ensure nutrient retention

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Splenic Protective Effect of White Turmeric Extract Against Copper Toxicity in Male Wistar Rats

Cited by 2 publications

References 11 publications

In Vitro and In Vivo Antidiarrheal Activity of Dragon Fruit Peels Methanolic Extract

In Vitro and In Vivo Antidiarrheal Activity of Dragon Fruit Peels Methanolic Extract

Antioxidant Activities, Phenolic Compounds and Organic Acids of Raw and Boiled Berries of Solanum Torvum Swartz From Eastern Côte d’Ivoire

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