Splenic infarction caused by a large thoracic aortic  thrombus

Md, Stefano F Agolini; Shah, Kamalesh; Goodreau, James J.; McLoughlin, Thomas M; Sinclair, Michael C.

doi:10.1016/s0741-5214(97)70022-3

Cited by 23 publications

(14 citation statements)

References 10 publications

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“…The aorta is becoming increasingly recognized as a source of systemic embolization with the detection of protruding atheromas and thrombi by transesophageal echocardiography (TEE). There are many reports that describe predominantly small aortic thrombi and atheromas [1][2][3][4][5]. These reports describe atheromas and thrombi in various portions of the aorta, with treatments including balloon embolectomy and anticoagulation therapy.…”

Section: Introductionmentioning

confidence: 99%

Surgical management of giant descending aortic thrombus detected by transesophageal echocardiography

Modi¹,

Longo²,

Kopf³

et al. 2000

Int J Angiol

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Section: Introductionmentioning

confidence: 99%

Surgical management of giant descending aortic thrombus detected by transesophageal echocardiography

Modi¹,

Longo²,

Kopf³

et al. 2000

Int J Angiol

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“…Potential causes include trauma, malignancy, hypercoagulable states (factor V Leiden mutation, polycythemia, antithrombin III deficiency, protein C and/or S deficiency, etc.) and autoimmune disorders [2, 8–10]. Other risk factors including the presence of microscopic atherosclerotic disease (difficult to exclude clinically), smoking, and oral contraceptive use should also be addressed in patients as appropriate.…”

Section: Discussionmentioning

confidence: 99%

Peripherally Embolizing Aortic Thrombus: The Work-Up, Management, and Outcome of Primary Aortic Thrombus

Mando

Gemayel

Chaddha

et al. 2019

Case Reports in Cardiology

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Background. Primary aortic thrombus is an uncommon entity and not frequently reported in the literature. Herein, we discuss the presentation and management of a patient with a primary thoracic mural thrombus. Case Summary. A 46-year-old female with past medical history of tobacco dependence presented for low-grade fever and sudden onset, severe right upper quadrant abdominal pain with associated nausea and vomiting. Computed tomography (CT) revealed an intraluminal polypoid filling defect arising from the isthmus of the aorta projecting into the proximal descending aorta and findings consistent with infarction of the spleen and right kidney. Infectious, autoimmune, hematologic, and oncologic work-up were all unyielding. The patient was started on heparin and later transitioned to apixaban 5 mg twice a day and 81 mg of aspirin daily. She was also counseled regarding smoking cessation. Two months follow-up CT revealed resolution of the thrombus. Patient had no further thromboembolic complications. Discussion. We present a unique case of primary aortic thrombus. To our knowledge, this is the first reported case managed successfully with a NOAC. This diagnosis is one of exclusion and through work-up should be completed. Our aim is to raise awareness of this condition and successful management with apixaban in low-risk patients.

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“…14 Frequently, patients present with acute lower limb ischemia. 6 In some other patients, aortic thromboembolism can be manifested by stroke, 15 myocardial infarction, 16 and splenic, 11,17 renal, 17,18 or intestinal infarct, 19 and others have been found incidentally in patients receiving imaging studies for unrelated conditions. 20 Diagnosis of thoracic and abdominal thrombosis can be made using CT and magnetic resonance angiography, as well as transthoracic and transesophageal echocardiography.…”

Section: Discussionmentioning

confidence: 99%

A Unique Case of Aortic Thrombosis With Elevated Lipoprotein(a)

Ostertag‐Hill

Titus

Skeik

2016

Vasc Endovascular Surg

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Aortic thrombosis is a rare condition that can be caused by atherosclerosis, aneurysms, thrombophilia, vasculitis, trauma, and malignancy. Symptoms vary based on thrombus size and site of embolization. It can lead to devastating complications including acute limb ischemia, myocardial infarction, stroke, and other target organ ischemia. Diagnosis is based on clinical presentation, imaging findings, and relevant laboratory work-up. Although not well defined, management for aortic thrombosis includes surgical intervention, such as thromboembolectomy, and conservative measures, such as anticoagulation. Here, we present a unique case of aortic thrombosis causing acute lower limb ischemia with elevated lipoprotein(a) and other comorbidities. Based on our literature review, our article is the first to establish the connection between elevated lipoprotein(a) and aortic thrombosis in the nonaneurysmal aorta.

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Splenic infarction caused by a large thoracic aortic thrombus

Cited by 23 publications

References 10 publications

Surgical management of giant descending aortic thrombus detected by transesophageal echocardiography

Surgical management of giant descending aortic thrombus detected by transesophageal echocardiography

Peripherally Embolizing Aortic Thrombus: The Work-Up, Management, and Outcome of Primary Aortic Thrombus

A Unique Case of Aortic Thrombosis With Elevated Lipoprotein(a)

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