1996
DOI: 10.1002/hep.510230515
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Splenic Doppler impedance indices: Influence of different portal hemodynamic conditions

Abstract: The spleen plays a pivotal role in the pathogenesis and maintenance of portal hypertension. Few data exist about splenic hemodynamics evaluated by duplex sonography in this condition. Twenty-six normal subjects, 207 patients with portal hypertension of various causes, and in different splenoportal hemodynamic conditions, and 31 patients with liver transplantation were evaluated. In each patient the splenic resistive index (RI = peak systolic--end diastolic velocity/peak systolic velocity) and pulsatility index… Show more

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Cited by 94 publications
(68 citation statements)
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References 24 publications
(1 reference statement)
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“…The causes of the increased spleen volume in cirrhosis are not clearly defined. Previous studies failed to establish a correlation between PP and splenomegaly,3, 6, 30, 31 although a direct correlation between spleen volume and portal vein diameter was reported 6. However, in our study, in which spleen volume was calculated in a more accurate way than just assessing the spleen diameter by ultrasonography and in which PP was carefully measured as the PPG, there was a significant correlation between spleen volume and baseline PPG.…”
Section: Discussionmentioning
confidence: 97%
“…The causes of the increased spleen volume in cirrhosis are not clearly defined. Previous studies failed to establish a correlation between PP and splenomegaly,3, 6, 30, 31 although a direct correlation between spleen volume and portal vein diameter was reported 6. However, in our study, in which spleen volume was calculated in a more accurate way than just assessing the spleen diameter by ultrasonography and in which PP was carefully measured as the PPG, there was a significant correlation between spleen volume and baseline PPG.…”
Section: Discussionmentioning
confidence: 97%
“…Recipients and donors were examined by color Doppler ultrasound with a GE Logiq Book color Doppler ultrasound diagnostic apparatus with a 3.5‐MHz sector electronic probe preoperatively and on postoperative days (PODs) 1, 3, 5, 7, 30, and 90 after LDLT. Monitoring indices included the following: (1) PBV, which was measured as the mean of the maximal velocity of the portal vein multiplied by a coefficient of 0.57, and (2) PBF, which was obtained by multiplication of the portal vein cross‐sectional area by PBV under the assumption of a circular shape of the portal vein section, as previously reported 8, 9. All measurements were randomly performed by 1 of 2 operators.…”
Section: Methodsmentioning
confidence: 99%
“…Interobserver and intraobserver variability of splanchnic echo‐Doppler measurements in our center has already been reported 12, 14, 17…”
Section: Methodsmentioning
confidence: 65%
“…Portal blood flow velocity (PBV) was evaluated as the time‐averaged maximum velocity multiplied by the coefficient 0.57, assuming the portal velocity profile to be parabolic, as previously reported 11, 12. Portal blood flow volume (PBF) was obtained by multiplication of the portal vein cross‐sectional area, assuming a circular shape of the portal vein section, by PBV 11, 12. The arterial Doppler resistance indices were measured as pulsatility index (PI) = (peak systolic velocity − end diastolic velocity)/mean velocity 13.…”
Section: Methodsmentioning
confidence: 99%
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