Splenic Abscess due to Brucella Melitensis − A Rare Pediatric Complication

Parande, Aisha M; Mantur, BG; Kore, M. S.; Palled, Eranna R

doi:10.4103/0974-2727.72212

Cited by 5 publications

(6 citation statements)

References 8 publications

(9 reference statements)

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“…The mortality rate of splenic abscess is reported to be 100% without treatment [ 16 ]. The prognosis of splenic abscess(es) is good with early diagnosis and treatment [ 17 ]. Although the therapy for uncomplicated brucellosis is well established, the best regimen for the treatment of localized lesions has not been clearly defined.…”

Section: Discussionmentioning

confidence: 99%

A 28-Year-Old Woman with Fever, Weight Loss, Pancytopenia, and Multiple Hepatosplenic and Bone Lesions

Sheybani

Amiri

Naderi

et al. 2015

Case Reports in Infectious Diseases

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Brucellosis is a systemic zoonotic infection that can involve any organ or system in the body. It may present with a broad spectrum of clinical manifestations. Considering such myriad presentations, brucellosis should always be considered in the differential diagnosis of any febrile illness in a compatible epidemiological context. Here, we report a rare presentation of acute brucellosis with multifocal osteomyelitis and hepatosplenic lesions.

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Section: Discussionmentioning

confidence: 99%

A 28-Year-Old Woman with Fever, Weight Loss, Pancytopenia, and Multiple Hepatosplenic and Bone Lesions

Sheybani

Amiri

Naderi

et al. 2015

Case Reports in Infectious Diseases

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“…Our patient also had hepatosplenomegaly when she administered. Our research showed only one pediatric case presented with hepatosplenic abscess in the course of infection, whose findings were seen in acute form of the disease and there is two pediatric cases presenting with splenic abscess formation [6][7][8]. Nodule or abscess formation was reported as chronic phase of the disease.…”

Section: Discussionmentioning

confidence: 99%

“…There is one pediatric case presenting with hepatosplenic abscess in the literature, cured with surgical drainage and two pediatric cases with splenic abscess that were cured with antibiotics [4][5][6][7][8]. As to our knowledge our case was the first pediatric patient that brucellosis causing both hepatic and splenic nodules in acute form of the disease.…”

Section: Introductionmentioning

confidence: 92%

Brucelloma; a case with hepatosplenic nodules Resolved with antibiotherapy

Balcı¹,

Akpinar²,

Ergin³

et al. 2014

Pau Med J

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Liver and spleen involvement are a common finding in the course of brucellosis; however, only one pediatric case with hepatosplenic and two pediatric cases with splenic abscess formation have been reported in the literature. Splenic abscess respond to treatment with anti-biotherapy but hepatosplenic abscess need surgical drainage as well. We present a case of a fourteen-year-old girl, with both hepatic and splenic nodule formation, and was cured with just anti-biotherapy. To our knowledge, this was the first pediatric case with hepatosplenic nodule to be cured with just combination anti-biotherapy.Pam Med J 2014;7(3):226-228

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“…Thirty per cent of infections can result in localized infection ( Aygen et al , 2002 ; Hasanjani Roushan et al , 2004 ) of which splenic abscesses represent a small minority of that. In the paediatric group, there are only two documented cases ( Vallego et al , 1996 ; Parande et al , 2010) .…”

Section: Introductionmentioning

confidence: 99%

An unusual case of seronegative, 16S PCR positive Brucella infection

Bharathan¹,

Backhouse

Rawat

et al. 2016

JMM Case Reports

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Introduction:Brucella is a zoonotic infection commonly diagnosed by isolation of the organism from blood culture or positive serological testing. It is an uncommon cause of a pyrexia of unknown origin in the United Kingdom.Case presentation: We describe the case of a 14-year-old girl with no history of travel who presented with pyrexia, weight loss, arthralgia, multiple splenic abscesses and a subsequent pleural effusion, the latter of which isolated a Brucella species on 16S rRNA PCR. The patient responded well to initiation of treatment for brucellosis and on repeat imaging, after 3 months, the splenic abscesses had resolved.Conclusion: This unique case demonstrates uncommon complications of brucellosis and the challenges of diagnosing the organism, the latter of which can be alleviated by the utilization of molecularbased technologies. This patient had a negative serology result for brucellosis, which highlights the need to interpret serology results with caution in non-endemic regions for brucellosis.

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Splenic Abscess due to Brucella Melitensis − A Rare Pediatric Complication

Abstract: Splenic abscess due to Brucella species is an extremely rare complication especially in acute illness. Here we report a case of splenic abscess caused by Brucella melitensis biotype 1 in a child with acute infection who was successfully treated with only antibiotics.

Cited by 5 publications

References 8 publications

A 28-Year-Old Woman with Fever, Weight Loss, Pancytopenia, and Multiple Hepatosplenic and Bone Lesions

A 28-Year-Old Woman with Fever, Weight Loss, Pancytopenia, and Multiple Hepatosplenic and Bone Lesions

Brucelloma; a case with hepatosplenic nodules Resolved with antibiotherapy

An unusual case of seronegative, 16S PCR positive Brucella infection

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