Splanchnic Vein Thrombosis in Acute Pancreatitis

Abstract

Splanchnic vein thrombosis occurred in 1.8% patients of AP. The use of AC was reasonably safe with no fatal bleeding complications. However, there was no significant difference in the recanalization rates in those with and without AC.

Role of Thrombophilia in Splanchnic Venous Thrombosis in Acute Pancreatitis

“…The reported incidence of SVT in previous studies ranged from 1.8-36.5% [6][7][8][9][17][18][19]. In our cohort of 96 patients, SVT was found in 26 (27.1%) patients.…”

“…Though the need for percutaneous catheter drainage was more common in patients with SVT compared to those without SVT, the difference did not reach the statistical significance. Earlier studies have reported that patients with SVT have longer hospital stays compared to those without [6][7][8][9][17][18][19]. Mortality as a direct consequence of SVT has not been reported in patients with AP, although SVT has a high mortality outside the setting of AP [21,22].…”

“…Ours is the largest study looking into lupus anticoagulant, β2GPI, anticardiolipin antibody, and FVL mutation analysis. These procoagulant parameters have previously been evaluated in only a small number of AP patients with SVT [7].…”

“…There is wide variation in the incidence of SVT in AP between different studies, with reported frequencies ranging from as low as 1.8% to as high as 36.5% [6][7][8][9]. Several studies have looked at the pathophysiological mechanisms associated with SVT [8][9][10].…”

The management of the patient with acute pancreatitis: from evidence to clinical practice

“…If it occurs in the context of a large necrotic area, it requires a specialized surgical approach. 136 …”