Spitz and Reed nevi: acquired or congenital?

Bär, Michael

doi:10.5826/dpc.0203a05

Cited by 5 publications

(3 citation statements)

References 34 publications

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“…SN are benign melanocytic lesions mostly identified by characteristic clinical and dermoscopic features. Although histopathological and dermoscopic criteria of SN have been considerably described, differential diagnosis of SN and MM is challenging [ 12 – 14 ]. In our study, most SN and MM in dermoscopy presented a “starburst” type of architecture ( Figure 4 A ).…”

Section: Discussionmentioning

confidence: 99%

Spitz nevus and melanoma: evaluation with dermoscopy and reflectance confocal microscopy

Pogorzelska-Antkowiak¹,

Słowińska²,

Farinazzo³

et al. 2023

pdia

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Introduction: Spitz nevi (SN) include a wide range of benign melanocytic nevi, which are controversial due to their morphologic resemblance to melanoma (MM). Aim: To describe dermoscopic and reflectance confocal microscopic (RCM) features of SN compared to MM and assess the RCM utility in the differential diagnosis. Material and methods: We performed a multicentre retrospective analysis of MM and SN evaluated with dermoscopy and reflectance confocal microscopy. Three RCM mosaics were obtained for each lesion. Nine dermoscopic and twenty-one microscopic features were assessed for each lesion. Results: A total of 26 lesions (15 SN and 11 MM) were included. Dermoscopically, most SN showed a "starburst" pattern. Asymmetry was marked in 8 MM. There were 6 dermoscopic features significantly more prevalent in MM than in SN. RCM showed that an atypical honeycomb pattern, atypical infiltration, and disarray of the epidermis were significant for MM. SN mostly revealed a typical honeycomb pattern. At the DEJ, most of SN had a meshwork pattern; MM revealed an atypical meshwork pattern. Atypical cells and sheet-like structures were observed in most MM. Conclusions: A combined approach using dermoscopy and RCM supports the differential diagnosis of SN and MM. Although our study showed some significant differences between SN and MM in RCM, further research on a larger group should be considered.

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Section: Discussionmentioning

confidence: 99%

Spitz nevus and melanoma: evaluation with dermoscopy and reflectance confocal microscopy

Pogorzelska-Antkowiak¹,

Słowińska²,

Farinazzo³

et al. 2023

pdia

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“…In reflectance confocal microscopy, the majority of Spitz nevi present a sharp border cutoff. The confocal image depends on a dermoscopic pattern of Spitz nevus 6–9 . A prevalent starburst pattern mostly reveals a typical honeycombed pattern of the epidermis and only a few pagetoid cells.…”

Section: Aim Of the Studymentioning

confidence: 99%

Mimics of melanoma in reflectance confocal microscopy

Pogorzelska-Antkowiak¹,

Calik²

2020

Int J Dermatology

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The diagnosis of melanoma is challenging for both dermatologists and oncologists. Incidence of melanoma increases at a rate of 3–7% per year. Usage of modern tools such as dermoscopy and in vivo reflectance confocal microscopy improve early diagnosis and can save a life. There are a few melanoma simulators which can cause confusion and mislead in the differential diagnosis. This study aims to present skin lesions which can be similar to melanoma in confocal microscopy and to emphasize the importance of a detailed differential diagnosis. We describe five melanocytic lesions similar to melanoma and misleading confocal features. Although in vivo reflectance confocal microscopy is very useful in differentiating melanocytic lesions, histopathology evaluation in cases of melanoma mimics is definitive.

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“…In the IDS guidelines 6 “Reed” and “Spitz” names are used interchangeably since a pathological distinction between the two entities cannot be made [ 9 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

Stardust Pattern As Evolution Of Pigmented Spitz Nevi During Childhood

Brunetti¹,

Briatico²,

Scharf³

et al. 2023

Dermatol Pract Concept

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Introduction: Spitz nevi (SN) are benign melanocytic proliferations frequently occurring in children. Some pigmented SN with starburst pattern evolve into the “stardust” one, which is characterized by a central, black to gray, hyperpigmented area and remnants of a brown network at the periphery. These dermoscopy changes are often the first alert to induce excision. Objectives: The aim of this study is to enlarge the case series of stardust SN in children, in order to increase confidence with this new dermoscopic pattern and reduce unnecessary excisions. Methods: This retrospective observational study was conducted with SN cases received from IDS members. The inclusion criteria were: clinical and/or histopathologic diagnosis of Spitz naevus with starburst appearance in children <12 years old, availability of a dermoscopic image at baseline and after follow-up of at least 1 year, availability of patient’ data. The dermoscopic images and their changes over time were assessed by three evaluators in consensus. Results: 38 SN were enrolled, with median age of 7 years and median FUP duration of 15,5 months. Comparing the evolution with time of FUP, no significant differences were found between growing and involuting lesions in terms of patient age and sex, location and palpability of lesions. Conclusions: The long follow up reported in our study could really support the concept of benignity of changing SN. A conservative approach is acceptable for nevi showing the stardust pattern, because it may be considered a physiological evolution of pigmented Spitz nevus, and urgent surgeries could be avoided.

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Spitz and Reed nevi: acquired or congenital?

Cited by 5 publications

References 34 publications

Spitz nevus and melanoma: evaluation with dermoscopy and reflectance confocal microscopy

Spitz nevus and melanoma: evaluation with dermoscopy and reflectance confocal microscopy

Mimics of melanoma in reflectance confocal microscopy

Stardust Pattern As Evolution Of Pigmented Spitz Nevi During Childhood

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