Spirometric Studies in Normal Subjects I

Berglund, Erik; Birath, G; Bjure, J.; Grimby, Gunnar; Kjellmer, Ingemar; Sandqvist, L.; Söderholm, B

doi:10.1111/j.0954-6820.1963.tb16520.x

Cited by 571 publications

(13 citation statements)

References 9 publications

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“…Previous studies have also suggested that normal respiratory function levels vary according to gender [30,31] and the CPF of male participants has been shown to be significantly higher than that of female participants [32]. Therefore, we hypothesized that gender can affect the coefficients in the estimation equation; however, no significant difference in estimation accuracy was found between male and female participants.…”

Section: Discussionmentioning

confidence: 86%

“…In the respiratory function test, participant height is generally used to determine the normal level of respiratory function [30,31] and a relationship between CPF and height has been reported [32]. Based on these previous studies, we hypothesized that height affects CPS ; however, in Equation (2), in which the coefficient α of Equation (1) was replaced by a linear function of height, the 95% CI of the multiplication coefficient α 1 onto the height ranged from −0.112 to 0.02, including 0.…”

Section: Discussionmentioning

confidence: 99%

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Estimation of Cough Peak Flow Using Cough Sounds

Umayahara

Soh

Sekikawa

et al. 2018

Sensors

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Cough peak flow (CPF) is a measurement for evaluating the risk of cough dysfunction and can be measured using various devices, such as spirometers. However, complex device setup and the face mask required to be firmly attached to the mouth impose burdens on both patients and their caregivers. Therefore, this study develops a novel cough strength evaluation method using cough sounds. This paper presents an exponential model to estimate CPF from the cough peak sound pressure level (CPSL). We investigated the relationship between cough sounds and cough flows and the effects of a measurement condition of cough sound, microphone type and participant’s height and gender on CPF estimation accuracy. The results confirmed that the proposed model estimated CPF with a high accuracy. The absolute error between CPFs and estimated CPFs were significantly lower when the microphone distance from the participant’s mouth was within 30 cm than when the distance exceeded 30 cm. Analysis of the model parameters showed that the estimation accuracy was not affected by participant’s height or gender. These results indicate that the proposed model has the potential to improve the feasibility of measuring and assessing CPF.

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Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

Estimation of Cough Peak Flow Using Cough Sounds

Umayahara

Soh

Sekikawa

et al. 2018

Sensors

View full text Add to dashboard Cite

show abstract

“…Since the lung function values were adjusted for age and sex by the use of reference values (16,17), these factors were not considered as potential confounders, but only atopy and smoking were used to adjust the effect estimates. All models were adjusted for these factors unless otherwise stated.…”

Section: Discussionmentioning

confidence: 99%

Lung Function in Relation to 2-Thiothiazolidine-4-Carboxylic Acid and Genetic Effect Modification Among Rubber Workers in Sweden

Jönsson

Littorin

Axmon

et al. 2008

Journal of Occupational &Amp; Environmental Medicine

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were 159 rubber exposed and 118 not-rubber exposed workers. Lung function was analyzed as forced vital capacity percent of predicted and forced expiratory volume in 1 second percent of predicted. Levels of 2-thiothiazolidine-4-carboxylic acid (a marker of carbon disulfide and vulcanization fumes) was assessed with liquid chromatography tandem mass spectrometry.Polymorphisms in glutathione-related genes were analyzed by Taqman-based allelic discrimination and ordinary polymerase chain reaction. Results: There was an association between increasing levels of 2-thiothiazolidine-4-carboxylic acid and impaired lung function among exposed workers. The association was modified by glutathione S-transferase alpha 1 (GSTA1)-52 and GSTP1-114. GSTM1 had an influence on lung function among unexposed workers. Conclusions: There may be a risk of impaired lung function in contemporary rubber workers. Gene-modifying effects may be considered in risk assessments.3

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“…Lung volumes were determined by the helium gas dilution method, and diffusing capacity for carbon monoxide (D LCO ) was measured by the single-breath method. The values obtained were expressed as a percentage of the predicted values [15]. Arterial blood samples obtained in room air were analyzed by a standard blood gas analyzer (ABL800, Radiometer Corp., Copenhagen, Denmark).…”

Section: Methodsmentioning

confidence: 99%

Distribution of Bone Mineral Content Is Associated with Body Weight and Exercise Capacity in Patients with Chronic Obstructive Pulmonary Disease

Yamamoto

Yoshikawa

Tomoda³

et al. 2013

Respiration

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Background: Although low bone mineral density is highly prevalent in patients with chronic obstructive pulmonary disease (COPD), the distribution of the reduced bone mass has not been fully elucidated. Objectives: To determine regional bone mass loss in patients with COPD and investigate whether the change in distribution may be associated with body weight loss and functional capacity. Methods: Body mass index (BMI) was assessed, and height squared indices were derived for the bone mineral content index (BMCI) of the arms, legs and trunk by dual-energy X-ray absorptiometry in 45 male patients with COPD and 12 age- and sex-matched control subjects. Pulmonary function tests were performed, and maximal oxygen uptake (V·O₂max) was measured. Results: The BMCI was lower in the total bone, legs and trunk of patients with COPD than in control subjects, although the BMCI in the arms was similar between the groups. BMI correlated significantly with the BMCI in all 3 segments. Bone mineral content (BMC) in the trunk, expressed as a percentage of total BMC (BMC trunk/total BMC), correlated significantly with BMI. The BMCI in the trunk was closely related with V·O₂max but not with airflow limitation. Conclusions: There was a regional difference in BMC reduction, but a predominant reduction of bone mass in the trunk was not associated with the severity of airflow limitation but rather with body weight loss and exercise intolerance. These data suggest that body weight loss and exercise intolerance are important risk factors for vertebral fracture in patients with COPD.

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Spirometric Studies in Normal Subjects I

Cited by 571 publications

References 9 publications

Estimation of Cough Peak Flow Using Cough Sounds

Estimation of Cough Peak Flow Using Cough Sounds

Lung Function in Relation to 2-Thiothiazolidine-4-Carboxylic Acid and Genetic Effect Modification Among Rubber Workers in Sweden

Distribution of Bone Mineral Content Is Associated with Body Weight and Exercise Capacity in Patients with Chronic Obstructive Pulmonary Disease

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