Spirometric profile of narghile smokers

Saad, Helmi Ben; Khemis, Mehdi; Bougmiza, Iheb; Préfaut, Christian; Aouina, H.; Mrizek, Najib; Garrouche, A.; Zbidi, A.; Tabka, Zouhaïr

doi:10.1016/j.rmr.2008.10.001

Cited by 26 publications

(32 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Studies analyzing ENS lung function are rare, have several methodological limits, and have yielded conflicting results (1, 2, 7, 18) (Supplementary file). A systematic review and meta-analysis of the chronic effects of narghile use on lung function (7) found no studies on the association of narghile smoking with airways diseases in general, and with chronic obstructive pulmonary disease (COPD) in particular.…”

Section: Discussionmentioning

confidence: 99%

“…To the best of our knowledge, studies of the lung function of exclusive narghile smokers (ENS) are few (10–19). These studies evaluating the chronic effects of narghile use on lung function present contradictory conclusions: lack of ventilatory defects (13, 14, 17), minimal (11) to significant (15, 16, 18) small-airways-obstructive-ventilatory-defect (SAOVD), large-airways-obstructive-ventilatory-defect (LAOVD) (10, 12, 15, 16, 18), restrictive-ventilatory-defect (RVD) (18), high frequency of lung hyperinflation (18), and acceleration of lung ageing with a significantly higher estimated-lung-age (ELA) when compared to chronological-lung-age (CLA) (18). …”

mentioning

confidence: 99%

“…The majority of these studies (10–18) used limited methodology such as low sample sizes (12, 14, 17) or inclusion of mixed cigarette and narghile smokers (10) or inclusion of elderly subjects aged more than 60, who probably suffer from co-morbidities that could influence lung function (11, 15). In addition, some studies measured only expiratory flows (10–17) and not lung volumes.…”

mentioning

confidence: 99%

“…In addition, some studies measured only expiratory flows (10–17) and not lung volumes. Furthermore, there is a lack of comparison with exclusive cigarette smokers (ECS) or healthy non-smokers (18). …”

mentioning

confidence: 99%

See 3 more Smart Citations

Pulmonary functions of narghile smokers compared to cigarette smokers: a case–control study

Saad

Khemiss

Nhari

et al. 2013

Libyan Journal of Medicine

View full text Add to dashboard Cite

BackgroundStudies of the lung function profiles of exclusive narghile smokers (ENS) are few, have some methodological limits, and present contradictory conclusions. The present study aimed to compare the plethysmographic profiles of ENS with age- and height-matched exclusive cigarette smokers (ECS).MethodsMales aged 35–60 living in Sousse, Tunisia, who have been smoking narghile exclusively for more than 10 narghile-years (n=36) or cigarettes exclusively for more than 10 pack-years (n=106) were recruited to participate in this case–control study. The anthropometric and plethysmographic data were measured according to international recommendations using a body plethysmograph (ZAN 500 Body II, Meβgreräte GmbH, Germany). Large-airway-obstructive-ventilatory-defect (LAOVD) was defined as: first second forced expiratory volume/forced vital capacity (FEV1/FVC) below the lower-limit-of-normal (LLN). Restrictive-ventilatory-defect (RVD) was defined as total lung capacity < LLN. Lung hyperinflation was defined as residual volume > upper-limit-of-normal. Student t-test and χ2 test were used to compare plethysmographic data and profiles of the two groups.ResultsThe subjects in the ENS and ECS groups are well matched in age (45±7 vs. 47±5 years) and height (1.73±0.06 vs. 1.72±0.06 m) and used similar quantities of tobacco (36±22 narghile-years vs. 35±19 pack-years). Compared to the ENS group, the ECS group had significantly lower FEV1 (84±12 vs. 60±21%), FVC (90±12 vs. 76±18%), and FEV1/FVC (99±7 vs. 83±17%). The two groups had similar percentages of RVD (31 vs. 36%), while the ECS group had a significantly higher percentage of LAOVD (8 vs. 58%) and lung hyperinflation (36 vs.57%).ConclusionChronic exclusive narghile smoking has less adverse effects on pulmonary function tests than chronic exclusive cigarette smoking.

show abstract

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Pulmonary functions of narghile smokers compared to cigarette smokers: a case–control study

Saad

Khemiss

Nhari

et al. 2013

Libyan Journal of Medicine

View full text Add to dashboard Cite

show abstract

“…For instance, in the case of an FVC change, end-expiratory flow determined at a fixed percentage of FVC is no longer deemed valid and isovolume end-expiratory flows measured at the same absolute volume are used instead [21,22]. Alternatively, FVC is also used as an indicator of small airways function, more specifically of airway closure and trapped air beyond them [23,24,25,26]. Another way to identify the small airway content from forced expiration is by examining the density dependence of forced expiratory flows, comparing air and heliox [27,28,29].…”

Section: Spirometrymentioning

confidence: 99%

Physiological Measurement of the Small Airways

Verbanck¹

2012

Respiration

View full text Add to dashboard Cite

Noninvasive physiological measurements are reviewed that have been reported in the literature with the specific aim being to study the small airways in lung disease. This has mostly involved at-the-mouth noninvasive measurement of flow, pressure or inert gas concentration, with the intent of deriving one or more indices that are representative of small airway structure and function. While these measurements have remained relatively low-tech, the effort and sophistication increasingly reside with the interpretation of such indices. When aspiring to derive information at the mouth about structural and mechanical processes occurring several airway generations away in a complex cyclically changing cul-de-sac structure, conceptual or semi-quantitative lung models can be valuable. Two assumptions that are central to small airway structure-function measurement are that of an average airway change at a given peripheral lung generation and of a parallel heterogeneity in airway changes. While these are complementary pieces of information, they can affect certain small airways tests in confounding ways. We critically analyzed the various small airway tests under review, while contending that negative outcomes of these tests are probably a true reflection of the fact that no change occurred in the small airways. Utmost care has been taken to not favor one technique over another, given that most current small airways tests still have room for improvement in terms of rendering their content more specific to the small airways. One way to achieve this could consist of the coupling of signals collected at the mouth to spatial information gathered from imaging in the same patient.

show abstract