Spirometric function in children of Mexico City compared to Mexican‐American children

Abstract

We set out to describe the pattern of lung function growth in Mexican students from 8-20 years of age, using internationally accepted equipment and methodology, and to compare it to values reported for Mexican-American children. Out of a total of 6,803 students from primary school to high school studied cross-sectionally in the Mexico City metropolitan area, we selected 4,009 asymptomatic, nonobese, nonsmoker subjects to generate spirometric prediction equations. We describe regression equations for the main spirometric variables (log transformed) based on age, height, and weight, and separated for males and females. Spirometric function in the population studied was above that predicted for European (Quanjer et al. [1987] Pediatr Pulmonol 19:135-142) or Mexican-American children, for the same age, height, and gender. On average, forced expiratory volume in 1 sec (FEV(1)) in Mexican children was 9.5% above that of Europeans (Quanjer et al. [1987] Pediatr Pulmonol 19:135-142), 14% and 5% above Hispanics reported by (Coultas et al. [1988] Am Rev Respir Dis 138:1386-1392) and (Hsu et al. [1979] J Pediatr 95:14-23), respectively, and 5% above Mexican-Americans from the third National Health and Nutrition Examination Survey study. Similarly, FVC was 8%, 14%, 8%, and 5.6% above the figures predicted by the same authors. The largest errors of prediction of foreign equations occurred in extremely tall or short subjects, and therefore a single proportional adjustment is unfeasible.

Lack of association between genetic variation in G-protein-coupled receptor for asthma susceptibility and childhood asthma and atopy

“…Spirometric prediction equations from a Mexico City childhood population were used to calculate the percent predicted forced expiratory volume in 1 s (FEV 1 ). 29 Children were asked to hold asthma medications on the morning of the test.…”

Changes in the FEV1/FVC ratio during childhood and adolescence: an intercontinental study

“…All of the studies had received ethical approval from the appropriate governing bodies, and data were collected after written informed consent had been obtained from parents and, where appropriate, the subjects themselves. With the exception of the Australian data, details regarding the selection of subjects, type of equipment used and derivation of summary statistics for FEV1 and FVC have been described previously [6][7][8][21][22][23][24][25][26][27][28][29]. All of the data were derived from children without a history of current or past respiratory disease, and all were lifelong nonsmokers.…”

“…Data from healthy children and adolescents who had been studied in the Netherlands [21,22], North America (Caucasians, African-Americans and Mexican-Americans) [23], England [8,24], Germany and Austria [25], Mexico City [6], Iran [7], Oman [26], India [27], Tunisia [28], Hong Kong [29] and Australia (G.L. Hall, Respiratory Medicine, Princess Margaret Hospital, School of Paediatric and Child Health, University of Western Australia, Perth, Australia, personal communication) were collated.…”

“…It has also been suggested that the FEV1/FVC ratio falls with both increasing age and body height (Ht) [5][6][7][8].…”

Função pulmonar de crianças e adolescentes com bronquiolite obliterante pós-infecciosa

“…This was a cross-sectional study involving children and adolescents (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18) years of age) with PIBO, in Brazil and Chile. The participants were periodically monitored at one of two tertiary care pediatric pulmonology outpatient clinics: that of the Hospital da Criança Santo Antonio, located in the city of Porto Alegre, Brazil; or that of the Centro de Referencia de Salud del Hospital El Pino, located in the city of Santiago, Chile.…”