Spinel copper ferrite nanoparticles: Preparation, characterization and catalytic activity

Abstract

The magnetic CuFe2O4 nanoparticles have been synthesized and characterized by various spectroscopic methods, including X‐ray diffraction (XRD), O K, Cu and Fe K ‐edge X‐ray absorption near edge structure (XANES), energy dispersive X‐ray analysis (EDX), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The azide‐alkyne cycloaddition by the reaction of various phenylacetylenes with a mixture of benzyl halides and NaN3 and also three component (A3) coupling reaction of aldehyde, alkyne and amine catalyzed by CuFe2O4 nanoparticles under aerobic conditions led to the formation of the 1,4‐disubstituted‐1,2,3‐triazoles and propargylamines in excellent yields. The catalyst can be recovered by applying an external magnetic field for the subsequent cycloaddition reactions and reused without any tangible loss in catalytic efficiency.

An Overview of Recent Advances in the Applications of Click Chemistry in the Synthesis of Bioconjugates with Anticancer Activities

“…The cuprous triazolide ( I‐4 ) is afforded with the reduction of the copper center from +3 to +1. Finally, the cuprous triazolide obtains a proton from an alkyne substrate or another proton source to produce the triazole molecule (Scheme ) …”

Two different facile and efficient approaches for the synthesis of various N-arylacetamides via N-acetylation of arylamines and straightforward one-pot reductive acetylation of nitroarenes promoted by recyclable CuFe2O4 nanoparticles in water

“…Furthermore, compared with iron oxides, spinel ferrites provide flexibility to control both crystal structures and magnetic properties by choosing different non-iron metals in spinel ferrite backbone and controlling their molar concentrations. Among various type of spinel ferrite magnetic nanoparticles (MNPs), CuFe 2 O 4 nanocomposite, in addition to numerous applications, has shown satisfactory performance as the recyclable catalyst in various organic transformations such as synthesis of heterocyclic compounds [46][47][48][49][50][51][52], Ullmann C-O coupling reaction [53], direct synthesis of chemical structures containing both phenol ester and benzothiazole moieties via dehydrogenative coupling reactions [54], reduction of p-nitrophenol [55], one-pot odorless carbon-sulfur bond formation reactions [56], directed phenol/formamide coupling [57], synthesis of diaryl/aryl alkyl sulfides via cross-coupling process [58], S-arylation of thioureas by aryl halides [59], one-pot four-component Dakin-West reaction (synthesis of β-acetamido ketones) [60], Friedel-Crafts acylation [61], N-arylation of heterocycles [62], direct C-H amination of benzothiazoles [63], oxidative hydroxylation of arylboronic acids [64], palm oil methanolysis [65], oxidation of benzyl alcohol [66], synthesis of unnatural arundines [67], N-arylation of indole and imidazole with aryl halide [68], and so on.…”

The tumorigenic and therapeutic functions of exosomes in colorectal cancer: Opportunity and challenges

“…According to statistical reports, the survival rate of CRC patients is significantly linked to the cancer stage at diagnosis. Early diagnosis of CRC may increase the 5‐year survival rate by more than 90%, whereas CRC patients identified at the late stage represent about 7% of the 5‐year survival rate 11,12 . Therefore, precise and early diagnosis of cancer is the hallmark of CRC control and prevention.…”