Spindle cell melanoma: Incidence and survival, 1973‑2017

Xu, Zhe; Shi, Ping; Yibulayin, Feiluore; Feng, Lei; Zhang, Hao; Wushou, Alimujiang

doi:10.3892/ol.2018.9247

Cited by 13 publications

(24 citation statements)

References 31 publications

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“…Via the National Cancer Institute's SEER*Stat software (version 8.3.5; SEER 18 Regs Custom Data [with an additional treatment field], November 2017 Sub [1973-2015 varying] database), we identified 3,983 penile cancer patients with known marital statuses between January 1, 2004, and December 31, 2015. The SEER database covers approximately 28% of the US population and collects information on cancer patients, including demographic information, primary tumour locations, cancer stages, treatment modalities and survival times 11.…”

Section: Methodsmentioning

confidence: 99%

Marital Status and Survival in Patients with Penile Cancer

Mao¹,

Zhang²,

Huang³

et al. 2019

J. Cancer

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Purpose : We aimed to reveal the effects of marital status on survival outcomes in patients with penile cancer. Methods : Patients with penile cancer who were diagnosed between 2004 and 2015 were identified by using the Surveillance, Epidemiology and End Results (SEER) database. Kaplan-Meier and Cox regressions were used to analyse the effects of marital status on overall survival (OS) and cancer-specific survival (CSS). Results : Among 3,195 eligible patients with penile cancer, 1,951 (61.1%) patients were married, 365 (11.4%) were divorced or separated, 327 (10.2%) were widowed and 552 (17.3%) were single. The widowed patients had the worst OS median survival time (22 months) and CSS median survival time (23.5 months). Marital status was an independent prognostic factor for OS and CSS of penile cancer patients. The multivariate Cox regression showed that widowed patients exhibited the poorest OS (hazard ratio [HR]: 1.73; 95% confidence interval [CI]: 1.48-2.03, p < 0.001) and the poorest CSS (HR: 1.64; 95% CI: 1.144-1.279, p < 0.001) compared with married patients. Similar results were observed in our centre database and the subgroup analyses based on the SEER stage and grade. Conclusions : In our study, we found that marital status was an independent prognostic factor for survival in patients with penile cancer. Additionally, widowed patients had the lowest OS and CSS compared with married patients.

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Section: Methodsmentioning

confidence: 99%

Marital Status and Survival in Patients with Penile Cancer

Mao¹,

Zhang²,

Huang³

et al. 2019

J. Cancer

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“…DM is more commonly diagnosed in men with a 2:1 male to female ratio (Table ). DM patients also tend to be older compared with non‐DM patients by about 10 years on average, with a median age at diagnosis of approximately 69 years for DM patients . A recent analysis of the Surveillance, Epidemiology, and End Results (SEER) cancer database demonstrates a gradually rising incidence of DM from 1992 to 2007 .…”

Section: Epidemiology and Clinical Presentationmentioning

confidence: 99%

Desmoplastic melanoma

Nicolson

Han

2018

Journal of Surgical Oncology

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Desmoplastic melanoma (DM) is a rare melanoma variant that has unique biology and pathology compared with conventional melanoma (non-DM). Importantly, DM is classified into pure and mixed histologic subtypes, which have been correlated with outcomes. Management of DM broadly mirrors that of non-DM; however, there are unique considerations for DM that influence treatment approaches. This paper will provide a contemporary overview of this disease and will review the literature regarding the management of DM. K E Y W O R D Sdesmoplastic melanoma, outcomes, radiation therapy, sentinel lymph node biopsy (SLNB), surgery | PATHOLOGYThe original description of DM described the tumor as a "variant of spindle cell melanoma which produces or elicits the production of abundant collagen." 1,15 DM is today defined as a paucicellular

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“…Unlike conventional melanoma, it often forms a non‐specific, non‐pigmented nodule on the skin . It is therefore difficult to identify clinically at the early stages and hence metastasis is a known complication . Early detection and surgical removal of any forms of cutaneous melanoma increases the 5‐year relative survival rate to 98% .…”

Section: Discussionmentioning

confidence: 99%

Cutaneous spindle cell melanoma as seen on ultrasound: A rare case study

Taylor

2020

Sonography

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Currently, according to World Health Organization, 132 000 melanoma incidences have been reported globally each year. 1 Alarmingly, Australia followed by New Zealand was reported to have the highest rate of melanoma in 2018. 2 In Australia, cutaneous melanoma is the third most commonly diagnosed cancer in both men and women aged between 15 and 39 years old. 3 Risk factors include prolonged exposure to the ultraviolet radiation from the sun causing sun burn, indoor tanning, personal and/or family history of melanoma and the phenotypic characteristic of fair skin. 4,5 If detected early in a localised state, melanoma is treatable by local excision; however, it can metastasise rapidly and become life threatening. 5 The case below describes an imaging journey of a patient who was diagnosed with a spindle cell melanoma in her arm, and the role ultrasound can play in the diagnosis.

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Spindle cell melanoma: Incidence and survival, 1973‑2017

Cited by 13 publications

References 31 publications

Marital Status and Survival in Patients with Penile Cancer

Marital Status and Survival in Patients with Penile Cancer

Desmoplastic melanoma

Cutaneous spindle cell melanoma as seen on ultrasound: A rare case study

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