Spindle Cell Lipoma in the Posterior Third of the Tongue

Syed, Mubbasher; K, Ramachandran; Arif, Muhammad; Gunawardena, W J; Y, De' Silva; Davis, Bonnie; Rb, Denholm

doi:10.2310/7070.2006.0001

Cited by 7 publications

(6 citation statements)

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“…Lingual spindle cell lipomas are benign neoplasms managed adequately by local excision. The present series along with prior reports with known follow up information have shown no instances of tumor recurrence or aggressive biologic behavior [3,11,14,16,18,19,21]. On gross examination, spindle cell lipomas are well circumscribed neoplasms with a firmer consistency than ordinary lipomas.…”

Section: Discussionsupporting

confidence: 53%

“…Spindle cell lipomas are infrequently encountered in the oral region, with lingual examples of this entity in particular being distinctly rare. To our knowledge, only 24 cases of spindle cell lipoma involving the tongue have been reported in the English literature [3,5,[9][10][11][12][13][14][15][16][17][18][19][20][21]. The clinical and pathologic features of lingual spindle cell lipoma based on findings from the present series combined with previously published data are summarized in Table 3.…”

Section: Discussionmentioning

confidence: 80%

“…While most ordinary lipomas of the oral cavity involve the buccal mucosa, tongue or lip [1][2][3][4][5][6][7][8], lingual examples of spindle cell lipoma remain rare. The reported literature pertaining to spindle cell lipoma of the tongue is relatively sparse and comprised predominantly of single case reports and limited descriptions of small numbers of cases among larger series of lipomas of the oral cavity [3,5,[9][10][11][12][13][14][15][16][17][18][19][20][21]. In this study, we analyzed eight new cases of lingual spindle cell lipoma in order to further characterize the clinicopathologic features of this uncommon type of intraoral lipomatous tumor.…”

Section: Introductionmentioning

confidence: 99%

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Spindle Cell Lipoma of the Tongue: A Clinicopathologic Study of 8 Cases and Review of the Literature

Lau

Bishop

Thompson

2014

Head and Neck Pathol

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Spindle cell lipoma is a histologically distinct variant of lipoma characteristically arising in the subcutis of the posterior neck, upper back, or shoulder. Spindle cell lipomas infrequently occur within the oral cavity and, in particular, rarely involve the tongue. The clinical and pathologic features of eight cases of spindle cell lipoma affecting the tongue were analyzed. The study group included five men and three women ranging in age from 35 to 80 years (mean 57.4 years). Most lesions presented as either a painless or slowly growing lingual mass. The tumors were well circumscribed and characterized microscopically by a mixture of mature adipocytes, cytologically bland spindle cells, and interspersed bundles of thick collagen fibers in variable proportions. Myxoid stroma was a prominent feature in three lesions. The spindle cells were positive with CD34, while negative with S-100 protein, desmin, and smooth muscle actin. Treatment consisted of local excision in all cases. There have been no recurrences to date, with clinical follow up information available for all patients (range 11-118 months; mean 50.8 months). Lingual examples of spindle cell lipoma should be distinguished from other fat containing spindle cell neoplasms that can arise at this anatomic site.

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Section: Discussionsupporting

confidence: 53%

Section: Discussionmentioning

confidence: 80%

Section: Introductionmentioning

confidence: 99%

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Spindle Cell Lipoma of the Tongue: A Clinicopathologic Study of 8 Cases and Review of the Literature

Lau

Bishop

Thompson

2014

Head and Neck Pathol

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“…The most common clinical presentation reported (24/30) was “painless mass” with only 2/30 cases presenting with painful masses 13,25 . In addition, 3/30 cases reported eating or speech difficulties 19,21,29 . Of note, one case reported by Lau et al 25 .…”

Section: Discussionmentioning

confidence: 99%

Spindle cell lipoma of the tongue: First case report from the Gulf region and review of the literature

Mousa,

Nukaly,

Mohamed

et al. 2023

Clinical Case Reports

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“…There is a marked male predilection especially in the sixth decade which may be partly explained by androgen receptors reactivity [1]. Other rare reported sites of occurrence in the head and neck region include the face [2], suprasellar region [3], buccal fat pad [4], oesophagus [5], nasal vestibule [6], the tongue [7, 8], floor of mouth [9], vallecula [10] and parotid gland [11]. …”

Section: Discussionmentioning

confidence: 99%

Left Supraclavicular Spindle Cell Lipoma

Oladejo

Moorthy

et al. 2010

International Journal of Otolaryngology

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Background. Spindle cell lipoma (SCL) is a benign lipomatous tumour, typically occurring in the posterior neck, shoulder or upper back of elderly males. They compose of fat, CD34 positive spindle cells, and ropey collagen on a myxoid matrix. This case highlights a rare presentation of SCL and the need for pre-operative diagnosis. Case Report. A 63-year-old gentleman presented with a pre-existing left supraclavicular mass that had recently increased in size. FNA and CT Scans were performed and results discussed in the mutidisciplinary team meeting. Excisional biopsy was recommended. Radiology. CT neck showed a left supraclavicular mass of fatty density with fine internal septations. A low-grade liposarcoma could not be excluded. Histopathology. FNA was indeterminate. Histology of specimen showed bland spindle cells with no evidence of malignancy. Immuno-histochemistry showed SCL with CD34 positivity and negative staining on CDK4 and p16. Management. Excision biopsy of the mass was performed which was technically difficult as the mass invaginated around the brachial plexus. The patient recovered well post-operatively with no neurological deficits. Conclusion. Spindle cell lipoma is a rare benign tumour and a pre-operative diagnosis based on the clinical context, imaging and immuno-histochemistry is crucial to management.

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Spindle Cell Lipoma in the Posterior Third of the Tongue

Cited by 7 publications

References 0 publications

Spindle Cell Lipoma of the Tongue: A Clinicopathologic Study of 8 Cases and Review of the Literature

Spindle Cell Lipoma of the Tongue: A Clinicopathologic Study of 8 Cases and Review of the Literature

Spindle cell lipoma of the tongue: First case report from the Gulf region and review of the literature

Left Supraclavicular Spindle Cell Lipoma

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