Spinal tumors

Goethem, Johan Van; Hauwe, Luc van den; Özsarlak, Ö; Schepper, A. M. A. De; Parizel, Paul M.

doi:10.1016/j.ejrad.2003.10.021

Cited by 192 publications

(110 citation statements)

References 26 publications

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“…The spine is the most common bony site for musculoskeletal tumors. The majority of spinal malignancies are the result of metastases of other tumors in the body, mainly from breast, lung or prostate cancer [10]. Vertebral compression fractures occur in almost 25 % of all postmenopausal women and the prevalence of compression fractures linearly increases with advancing age, up to 40 % in women 80 years of age [11].…”

Section: Introductionmentioning

confidence: 99%

Red flags presented in current low back pain guidelines: a review

et al. 2016

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Objective The purpose of this study was to identify and descriptively compare the red flags endorsed in guidelines for the detection of serious pathology in patients presenting with low back pain to primary care. Method We searched databases, the World Wide Web and contacted experts aiming to find the multidisciplinary clinical guideline in low back pain in primary care, and selected the most recent one per country. We extracted data on the number and type of red flags for identifying patients with higher likelihood of serious pathology. Furthermore, we extracted data on whether or not accuracy data (sensitivity/specificity, predictive values, etc.) were presented to support the endorsement of specific red flags. Results We found 21 discrete guidelines all published between 2000 and 2015. One guideline could not be retrieved and after selecting one guideline per country we included 16 guidelines in our analysis from 15 different countries and one for Europe as a whole. All guidelines focused on the management of patients with low back pain in a primary care or multidisciplinary care setting. Five guidelines presented red flags in general, i.e., not related to any specific disease. Overall, we found 46 discrete red flags related to the four main categories of serious pathology: malignancy, fracture, cauda equina syndrome and infection. The majority of guidelines presented two red flags for fracture ('major or significant trauma' and 'use of steroids or immunosuppressors') and two for malignancy ('history of cancer' and 'unintentional weight loss'). Most often pain at night or at rest was also considered as a red flag for various underlying pathologies. Eight guidelines based their choice of red flags on consensus or previous guidelines; five did not provide any reference to support the choice of red flags, three guidelines presented a reference in general, and data on diagnostic accuracy was rarely provided. Conclusion A wide variety of red flags was presented in guidelines for low back pain, with a lack of consensus between guidelines for which red flags to endorse. Evidence for the accuracy of recommended red flags was lacking.

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Section: Introductionmentioning

confidence: 99%

Red flags presented in current low back pain guidelines: a review

et al. 2016

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“…Pain and motor patterns may obscure a systematic clinical presentation in these patients as high cervical lesions may present as occipital headache (McCormick et al, 1990), syringomyelia, and Brown-Séquard syndrome (Parsa et al, 2004), whereas thoracic neoplasms may be disguised as visceral pathology (McCormick et al, 1990). Less commonly, motor weakness, spasticity, sensory loss (hypoesthesia, paresthesia, or anesthesia), numbness, ataxic gait, or bowel and bladder dysfunction may be the initial presentation that arouses clinical attention (Gezen et al, 2000;King et al, 1998;Klekamp et al, 1999;Traul et al, 2007;Van Goethem et al, 2004). In this series, however, numbness and/or neurological deficits were frequent symptoms in patients with lumbar spinal meningioma.…”

Section: Clinicsmentioning

confidence: 99%

Management of Lumbar Spinal Meningioma: A Systematic Review

Hirabayashi¹

2012

Meningiomas - Management and Surgery

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“…Most lesions are extrameduallary, such as schwannoma and neurofibroma. Among spinal tumors, intramedullary tumors are uncommon, and most cases are astrocytoma and ependymoma [9] . MRI plays a central role in the diagnosis of these tumors [10] , and readily permits their classification.…”

Section: Right Leftmentioning

confidence: 99%

A patient with spinal metastasis from hepatocellular carcinoma discovered from neurological findings

Tamaki

Shimizu²,

Urata³

et al. 2007

WJG

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Although spinal tumors are uncommon, they may reduce survival or cause serious functional disorders in the extremities. Metastatic spinal tumors from malignant tumors can induce symptoms of spinal cord compression, such as paraplegia, quadriplegia, and vesicorectal disturbance, which are aggravated with progression of the diseases and time. We report a patient with hepatocellular carcinoma (HCC) who was suspected of having spinal lesions based on neurological findings, and a metastatic spinal tumor was found by imaging examination. Assuming that metastasis had occurred at the time lumbar pain developed, the patient reached the level of gait disturbance within only 4 mo, showing a rapid advancement of symptoms. If early diagnosis had been possible, treatment could be performed before acute myelopathy progressed to complete paralysis. We speculate that the terminal stage of HCC is not only liver failure associated with intrahepatic lesions but also metastasis to other regions, treatment for individual pathologies therefore, will be needed, which constitutes an important issue.

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Spinal tumors

Cited by 192 publications

References 26 publications

Red flags presented in current low back pain guidelines: a review

Red flags presented in current low back pain guidelines: a review

Management of Lumbar Spinal Meningioma: A Systematic Review

A patient with spinal metastasis from hepatocellular carcinoma discovered from neurological findings

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