2014
DOI: 10.1016/j.clineuro.2014.05.021
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Spinal tuberculosis at the posterior element of spinal column: Case report

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Cited by 3 publications
(3 citation statements)
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“…2 It is disseminated through the intercostal arteries, lumbar arteries and the vertebral venous plexus (Batson's plexus). 3 Tuberculosis causes the development of granulomatous inflammation that is characterised by the infiltration of lymphocytes and epithelioid cells. These cells may combine to form large Langhans-type giant cells and ultimately lead to caseating necrosis of the affected tissue, resulting in cold abscess formation.…”
Section: Discussionmentioning
confidence: 99%
“…2 It is disseminated through the intercostal arteries, lumbar arteries and the vertebral venous plexus (Batson's plexus). 3 Tuberculosis causes the development of granulomatous inflammation that is characterised by the infiltration of lymphocytes and epithelioid cells. These cells may combine to form large Langhans-type giant cells and ultimately lead to caseating necrosis of the affected tissue, resulting in cold abscess formation.…”
Section: Discussionmentioning
confidence: 99%
“…Early radiological diagnosis of posterior element TB is difficult even in high-burden regions, resulting in delayed diagnosis and even misdiagnosis in some cases. 12 This is compounded by the fact that spinal TB is characterized by a paucibacillary state, rendering them also difficult to prove by microbiological isolation of the causative agent. 6 , 11 As illustrated in this case report, the diagnosis is often based solely on histopathological findings consistent with granulomatous infection, such as the presence of epithelioid granulomas, caseation necrosis, lymphocytic infiltration, and/or presence of Langhans-type giant cells, which is seen in up to 56% of spinal TB cases.…”
Section: Discussionmentioning
confidence: 99%
“…Posterior-only approach is associated with relatively better clinical outcome in both adult and elderly population, but its feasibility is subjective to the accessibility of the distant focus, the degree of bone destruction, and the associated risk of injuring the iliac vessels, aorta, abdominals contents, and the spinal cord [6][7][8] . In cases with atypical presenting features where TB involved the posterior column or presented as non-contiguous lesions, multifocal, surgical approaches need to involve complete debridement with combinedanterior-posterior approaches 9,10 . Apart from the conventional surgical procedures mentioned above, some authors have also proposed new surgical techniques to treat conditions with certain characteristics.…”
Section: Discussionmentioning
confidence: 99%