Spinal interneuron population dynamics underlying flexible pattern generation
Lahiru N. Wimalasena,
Chethan Pandarinath,
Nicholas Au Yong
Abstract:The mammalian spinal locomotor network is composed of diverse populations of interneurons that collectively orchestrate and execute a range of locomotor behaviors. Despite the identification of many classes of spinal interneurons constituting the locomotor network, it remains unclear how the network’s collective activity computes and modifies locomotor output on a step-by-step basis. To investigate this, we analyzed lumbar interneuron population recordings and multi-muscle electromyography from spinalized cats… Show more
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