Spinal Cord Ischemia and Left Atrial Myxoma

Hirose, Genjiro; Kosoegawa, H; Takado, Matsuhei; Shimazaki, Kohei; Murakami, Eiji

doi:10.1001/archneur.1979.00500430069011

Cited by 22 publications

(7 citation statements)

References 2 publications

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“…In more than a half of the cases, the embolic event affects the CNS [9, 15], which occurred in our series in 82% of patients with embolic phenomena. Cerebral infarcts, TIA, amaurosis, and less frequently medullary infarcts [16]may be the clinical symptom. When cardiac myxomas are located in right cavities, they may produce pulmonary embolisms, hemoptysis or pulmonary hypertension [10, 17].…”

Section: Discussionmentioning

confidence: 99%

Transient Ischaemic Attack: A Common Initial Manifestation of Cardiac Myxomas

Álvarez-Sabín¹,

Lozano²,

Sastre‐Garriga³

et al. 2001

Eur Neurol

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Background and Aims: Cardiac myxomas may present clinically with many different features. Since highly effective treatments exist, it is important that they are diagnosed quickly in order to avoid further complications. Our aim was to determine the influence of neurological presentation in diagnosis and prognosis of cardiac myxomas. Methods: We have reviewed the clinical charts of 28 patients diagnosed with cardiac myxomas seen at our centre in the last 20 years. Results: Mean age at diagnosis in patients with neurological events was 49.22 years and 60.84 years in those without neurological manifestations (p = 0.0325). Most frequent presentations were: cardiac manifestations (92.8%), general manifestations (71.4%) and embolic events (39.3%). Nine patients (32.1%) presented with cerebral embolism; 7 of whom presented with transient ischaemic attacks (TIA), which was the first manifestation in 6 of them; 3 of them later suffered complete cerebral infarction with sequelae. Echocardiography confirmed diagnosis in 26 out of 27 patients in which it was performed. None of the patients presented neurological symptoms after surgery. Conclusion: The most frequent initial neurological manifestation in our series was TIA. Nevertheless, none of the patients were diagnosed after the first neurological symptom. Although the contribution of cardiac myxomas to the total amount of TIA is low, since surgery is highly effective and of low risk, and patients with neurological manifestations are younger, it is vital to consider the possibility of cardiac myxoma after a TIA of unknown origin.

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Section: Discussionmentioning

confidence: 99%

Transient Ischaemic Attack: A Common Initial Manifestation of Cardiac Myxomas

Álvarez-Sabín¹,

Lozano²,

Sastre‐Garriga³

et al. 2001

Eur Neurol

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“…15 Unlike the situation with cerebral embolic events, cardiogenic emboli rarely are involved. 1 6 Paraplegia due to spinal cord ischemia has been reported in two patients with left atrial myxomas, 17,18 however, to our knowledge it has not been a reported complication of cardiac papillarybroelastomas. The various pathophysiological causes in the differential diagnosis of embolic spinal cord ischemia (atheroemboli, thromboemboli, and tumor emboli) may be impossible to distinguish from one another.…”

Section: Discussionmentioning

confidence: 99%

Unusually Located Left Atrial Papillary Fibroelastoma with Probable Embolization to the Spinal Cord

et al. 2001

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This report presents a patient with flaccid paraplegia, most probably secondary to embolization from a left atrial papillary fibroelastoma. The unique location of the tumor, attached to the ridge in the left atrium between the left atrial appendage and pulmonary vein, was well documented on transesophageal echocardiography, and the diagnosis was confirmed by histopathology. Although benign, these tumors may develop in all four cardiac chambers and result in pulmonary or systemic embolization. Paraplegia is a rare embolic complication.

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“…These aneurysms can bleed causing subarachnoid hemorrhage or intracerebral bleed [5]. Other neurological manifestations of myxoma include psychiatric manifestations, headaches, seizures, coma and very rarely spinal cord embolism [6].…”

Section: Discussionmentioning

confidence: 99%

An unusual cause of stroke in a 55-year-old woman

Gokhale

Pfannl

Ramos-Estébanez

2013

International Journal of Neuroscience

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A 55-year-old woman presented with acute onset ataxia and right-sided dysmetria. Magnetic resonance imaging (MRI) confirmed clinical suspicion of stroke. She was found to have middiastolic murmur which led to urgent echocardiogram demonstrating left atrial myxoma. She underwent prompt surgical resection. Cardiac myxoma is a very rare cause of stroke. The presentation can be varied and diagnosis can be often missed. Early surgical intervention is a definitive treatment. Our case is unique and underlines importance of eliciting accurate physical signs at bedside.

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Spinal Cord Ischemia and Left Atrial Myxoma

Cited by 22 publications

References 2 publications

Transient Ischaemic Attack: A Common Initial Manifestation of Cardiac Myxomas

Transient Ischaemic Attack: A Common Initial Manifestation of Cardiac Myxomas

Unusually Located Left Atrial Papillary Fibroelastoma with Probable Embolization to the Spinal Cord

An unusual cause of stroke in a 55-year-old woman

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