Spinal Cord Injury Pain Instrument and pain<scp>DETECT</scp> questionnaire: Convergent construct validity in individuals with Spinal Cord Injury

Franz, Steffen; Schuld, Christian; Wilder-Smith, Einar; Heutehaus, Laura; Lang, Simone; Gantz, Simone; Schuh‐Hofer, Sigrid; Treede, R.‐D.; Bryce, Thomas N.; Wang, H.; Weidner, Norbert

doi:10.1002/ejp.1069

Cited by 19 publications

(15 citation statements)

References 42 publications

(89 reference statements)

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“…At the time the survey was conducted, while it showed promising psychometric properties (Bryce et al., ) its transferability to an unbiased SCI population remained in question. The SCIPI has more recently again shown high sensitivity, specificity and diagnostic accuracy in diagnosing SCI NP and should now be considered for inclusion in future prevalence studies in this population (Franz et al., ). Finally, whilst a full clinical examination to confirm a NP presentation is the gold standard, it was not feasible given the study design and a probable diagnosis of NP was thus conferred.…”

Section: Discussionmentioning

confidence: 99%

Quality of life after spinal cord injury: The impact of pain

Burke

Lennon

Fullen

2018

European Journal of Pain

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Section: Discussionmentioning

confidence: 99%

Quality of life after spinal cord injury: The impact of pain

Burke

Lennon

Fullen

2018

European Journal of Pain

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“…the numeric rating scale (NRS), the visual analogue scale (VAS), and the Likert-scale) (see statement 3.3). As opposed to the douleur neuropathique 4 questions (DN4), the spinal cord injury pain instrument (SCIPI), which was specifically developed for screening of SCI-related neuropathic pain, has recently been validated in German and is publicly available [ 163 ].…”

Section: Discussionmentioning

confidence: 99%

Management of pain in individuals with spinal cord injury: Guideline of the German-Speaking Medical Society for Spinal Cord Injury

Franz

Schulz

Wang

et al. 2019

GMS German Medical Science; 17:Doc05

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“…The European Multicenter Study About Spinal Cord Injury pain assessment form 70 71 and the Spinal Cord Injury Pain Instrument [72][73][74] are standardised and validated tools to evaluate pain in individuals with SCI.…”

Section: Pain Assessmentmentioning

confidence: 99%

Deep brain stimulation for locomotion in incomplete human spinal cord injury (DBS-SCI): protocol of a prospective one-armed multi-centre study

et al. 2021

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IntroductionSpinal cord injury (SCI) is a devastating condition with immediate impact on the individual’s health and quality of life. Major functional recovery reaches a plateau 3–4 months after injury despite intensive rehabilitative training. To enhance training efficacy and improve long-term outcomes, the combination of rehabilitation with electrical modulation of the spinal cord and brain has recently aroused scientific interest with encouraging results. The mesencephalic locomotor region (MLR), an evolutionarily conserved brainstem locomotor command and control centre, is considered a promising target for deep brain stimulation (DBS) in patients with SCI. Experiments showed that MLR-DBS can induce locomotion in rats with spinal white matter destructions of >85%.Methods and analysisIn this prospective one-armed multi-centre study, we investigate the safety, feasibility, and therapeutic efficacy of MLR-DBS to enable and enhance locomotor training in severely affected, subchronic and chronic American Spinal Injury Association Impairment Scale C patients in order to improve functional recovery. Patients undergo an intensive training programme with MLR-DBS while being regularly followed up until 6 months post-implantation. The acquired data of each timepoint are compared with baseline while the primary endpoint is performance in the 6-minute walking test. The clinical trial protocol was written in accordance with the Standard Protocol Items: Recommendations for Interventional Trials checklist.Ethics and disseminationThis first in-man study investigates the therapeutic potential of MLR-DBS in SCI patients. One patient has already been implanted with electrodes and underwent MLR stimulation during locomotion. Based on the preliminary results which promise safety and feasibility, recruitment of further patients is currently ongoing. Ethical approval has been obtained from the Ethical Committee of the Canton of Zurich (case number BASEC 2016-01104) and Swissmedic (10000316). Results will be published in peer-reviewed journals and presented at conferences.Trial registration numberNCT03053791.

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Spinal Cord Injury Pain Instrument and painDETECT questionnaire: Convergent construct validity in individuals with Spinal Cord Injury

Cited by 19 publications

References 42 publications

Quality of life after spinal cord injury: The impact of pain

Quality of life after spinal cord injury: The impact of pain

Management of pain in individuals with spinal cord injury: Guideline of the German-Speaking Medical Society for Spinal Cord Injury

Deep brain stimulation for locomotion in incomplete human spinal cord injury (DBS-SCI): protocol of a prospective one-armed multi-centre study

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