Spinal cord compression caused by a brown tumor secondary to primary hyperparathyroidism

Abstract

Background: Brown tumors (BTs) are rare non-neoplastic lesions that arise secondary to hyperparathyroidism largely involving mandible, ribs, pelvis, and large bones. Spinal involvement is extremely rare and may result in cord compression. Case Description: A 72-year-old female with the primary hyperparathyroidism developed a thoracic spine BT causing T3–T5 spinal cord compression warranting operative decompression. Conclusion: BTs should be included in the differential diagnosis in lytic-expansive lesions involving the spine. For those who develop neurological deficits, surgical decompression may be warranted followed by parathyroidectomy.

Brown Tumor of the Dorsal Spine With Hemorrhage Causing Acute Neurological Deterioration: A Rare Presentation of Secondary Hyperparathyroidism

“…The clinical presentation and imaging features of a brown tumor can masquerade as myeloma, blood dyscrasias, spine metastasis, giant cell tumors, and aneurysmal bone cysts [ 10 - 12 ]. The diagnosis mustn't be missed since it is a completely treatable benign problem with favorable outcomes [ 13 ]. In primary hyperparathyroidism, a biopsy of the brown tumor is required since that may be the first manifestation of the disease.…”