Spinal cord compression by extramedullary haematopoiesis in myelosclerosis

Pleural extramedullary haematopoiesis in myelosclerosis

“…Close, Taira & Cleveland (1958) describe a case of spinal cord compression demonstrated on myelography later shown to be due to extradural myeloid metaplasia associated with myelosclerosis. Similar cases have been reported by Lowman, Bloor & Newcomb (1963) and Appleby et al (1964).…”

Spinal cord compression by extramedullary haematopoiesis in myelofibrosis

“…The diagnosis of spinal cord compression by extramedullary haematopoiesis is confirmed by myelography, usually showing a complete block to the passage of contrast. Radiological changes in the bones at the level of the spinal cord lesion may be found (Appleby et aL, 1964), though not in our case. Treatment is by decompressive laminectomy and radiotherapy.…”

“…Neurological complications from extramedullary haematopoiesis in the cranial or spinal dura are rare and there are very few reports of this occurring in association with myelofibrosis (Appleby et al, 1964;Bree, Neiman and Hodak, 1974;Close, Taira and Cleveland, 1958;Lowman, Bloor and Newcomb, 1963;Oustwani et al, 1980). The origin of the extramedullary haematopoietic tissue within the spinal canal is unknown, but various possibilities have been suggested (Appleby et al, 1964;Heffner and Koehl, 1970;Oustwani et al, 1980). It may reach the epidural space by embolization from the marrow.…”

Extramedullary Hematopoietic Tumors of the Cranial Dura mater

“…Occasional cases have been recorded involving the anus [5] and testis [8]. Few cases have been reported involving the dura mater of the spinal canal and causing spinal cord compression [2,4,10,14]. In reviewing the literature we have found involvement of the cranial dura recorded on only 2 instances: In 1927, Brannan [3] described a nodular tumor mass in the cerebral falx of a 7 %-month-old infant with von Jaksch's anemia.…”