Spinal cord complications of acute schistosomiasis mansoni

Neves, Jorge Tadeu de Ramos; Marinho, Roberto Pedercini; Araujo, Paulo Kleber De; Raso, Pedro

doi:10.1016/0035-9203(73)90004-7

Cited by 29 publications

(8 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A current revision of the Brazilian and international literature, by Index-Medicus and Latin-American Index-Medicus, found 50 cases of SCS in children 7,[14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33] and the adult patients series by Galvão 11 and Peregrino et al 26 were compared with the authors' findings.…”

Section: Methodsmentioning

confidence: 99%

Spinal cord schistosomiasis in children: analysis of seven cases

Paz

Valente

Casella

et al. 2002

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

-We describe seven cases of children (ages 2 to 14 years) with myeloradiculopathy caused by infection with S. mansoni. None of them presented hepatosplenic involvement and one presented an intestinal picture. The myeloradicular and pseudotumoral forms were observed in four and three patients, respectively. Comparing the reports in the literature, we found that the pseudotumoral form is more similary frequent among children than in adults, while the myelitic and myeloradicular forms are the most frequent and distributed across all age groups. Diagnosis is based on clinical and epidemiological findings in association with laboratory tests. The diagnosis was confirmed by the presence of S. mansoni eggs in feces (5 cases) and / or the positivity in specific immunological tests (5 cases) associated with a cerebrospinal fluid inflammatory pattern with presence of eosinophils (between 1 and 24%). Magnetic resonance image, although it does not enable an etiological diagnosis, helped to confirm the form and spinal cord level of the lesion.KEY WORDS: schistosoma mansoni, spinal cord schistosomiasis, schistosomal myelopathy, myelitis, spinalcord pseudotumor, child. Esquistossomose medular em crianças: análise de sete casosRESUMO -Relatamos sete crianças com mielorradiculopatia devida a infecção pelo S. mansoni, com idade entre 2 e 14 anos. Nenhuma apresentou acometimento hepatoesplênico e uma apresentou quadro intestinal. A forma mielorradicular foi observada em quatro pacientes e a pseudotumoral em três. Revendo os achados da literatura, encontramos que a forma pseudotumoral é mais frequente nas crianças que nos adultos, apesar das formas mielíticas e mielorradiculares serem ainda as mais frequentes em todas as idades. O diagnóstico baseou-se nos achados clínicos e epidemiológicos, associados aos laboratoriais. A presença de ovos de S. mansoni nas fezes (5 casos) e/ou a positividade de testes imunológicos específicos no liquido cefalorraquidiano (5 casos), com padrão inflamatório e eosinofilorraquia (entre 1 e 24%) confirmou o diagnóstico. O estudo da imagem de ressonância magnética, apesar de não permitir o diagnóstico etiológico, ajudou a confirmar a forma e o nível medular da lesão. PALAVRAS-CHAVE: esquistosomose mansoni, esquistossomose medular, mielopatia esquistossomótica, mielite, pseudotumor medular, criança. . The prevalence of oviposition in the central nervous system (CNS) varies among studies from 0.3 to 30 percent of infected individuals [3][4][5] . It is generally myeloradicular and occasionally encephalitic, as opposed to Schistosomiasis japonica in which encephalitic involvement is more frequent. Many patients remain asymptomatic. Spinal cord schistosomiasis (SCS) is one of the most frequent causes of non-traumatic myelopathies, responsible for 6% of these in endemic areas 6 . Vascular lesions caused by SM appear to be responsible for the neurological sequels. Vascular obstruction in the spinal cord (SC) is secondary to the formation of a granuloma, with an intense inflammatory reaction and ischem...

show abstract

Section: Methodsmentioning

confidence: 99%

Spinal cord schistosomiasis in children: analysis of seven cases

Paz

Valente

Casella

et al. 2002

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

show abstract

“…Analysis of the cerebral spinal fluid of SMR patients reveals slight to moderate increases in protein content, lymphocytosis and eosinophils (Neves et al 1973, Braga et al 2003, 2004, SouzaPereira et al 2006, Lambertucci et al 2007b.…”

Section: Pyogenic Liver Abscessesmentioning

confidence: 99%

Acute schistosomiasis mansoni: revisited and reconsidered

Lambertucci

2010

Mem. Inst. Oswaldo Cruz

104

120

View full text Add to dashboard Cite

“…Most of these patients are asymptomatic, but recent infection can cause serious disease, such as Katayama fever or severe neurological complications involving the spinal cord (22,28).…”

mentioning

confidence: 99%