Spinal brucellosis: Turkish experience based on 452 cases published during the last century

Abstract

Based on this critical review of literature from Turkey, it is concluded that early diagnosis and correct management are important to prevent the harmful effects of brucellosis and its complications, and that the treatment of choice is antibiotic therapy alone in most cases of brucellosis involving the spine.

Skeletal evidence of brucellosis in a medicolegal context: A report of two cases

“…In the chronic phase the disease is characterized by various organ-related manifestations, bones and nerves [1]. It has been reported that skeletal manifestations are more frequent and more evident during the chronic and subacute stages [8,22,25,26]. According to Capasso in the initial phase there is a characteristic brucellar polyserositis with a pleural, peritoneal or pericardial seat [1].…”

“…Brucellosis is divided according to its duration into acute (less than 2 months), subacute (2-12 months), and chronic form (more than 12 months) [8]. Primary infection typically manifests as chronic respiratory illness, fever and splenomegaly [7].…”

Magnetic Resonance Imaging Findings of Pediatric Neurobrucellosis

“…Radiculopaty was most frequent neurological finding and spondylitis or spondylodiscitis was the predominant radiological finding. MRI was found to be more sensitive in detecting the presence of spondylodiscitis than other imaging modalities [12].…”

A Rare Case of Brucella Spondylodiscitis Mimicking Lumbar Disc Herniation

“…Spinal brucellosis originates through a haematogenous route and infection usually initiates from the anterior superior endplate of a vertebra corpus due to the rich supply of blood in this area [1,2]. Inflammation can then distribute to the entire vertebral body or to the intervertebral disc, causing spondylodiscitis.…”

“…Inflammation can then distribute to the entire vertebral body or to the intervertebral disc, causing spondylodiscitis. Literature regarding nerve root compression in brucellar spondylodiscitis involves complications such as epidural abscess, granuloma or discitis secondary to vertebral body involvement by brucellosis [1][2][3]. Brucellosis discitis as an infectious etiology of spinal root compression is uncommon.…”