Spinal and supraspinal effects of activity in ligament afferents

Sjölander, Per; Johansson, Håkan; Djupsjöbacka, Mats

doi:10.1016/s1050-6411(02)00017-2

Cited by 152 publications

(110 citation statements)

References 68 publications

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“…This afferent input has a strong effect on the ␥-motoneuron system that provides continuous preparatory adjustments to muscle stiffness (31)(32)(33)(34). Higher muscle stiffness may increase the responsiveness of muscles, a speculation that is supported by our data indicating significantly greater frequencies of responses in the medial hamstrings and sartorius muscles in the OA group.…”

Section: Discussionmentioning

confidence: 56%

Knee stabilization in patients with medial compartment knee osteoarthritis

Lewek¹,

Ramsey²,

Snyder‐Mackler³

et al. 2005

Arthritis & Rheumatism

111

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Objective. Individuals with medial knee osteoarthritis (OA) experience knee laxity and instability. Strategies aimed at muscle stabilization may influence the long-term integrity of the joint. This study sought to determine how individuals with medial knee OA respond to a rapid valgus knee movement, to investigate the relationship between muscle-stabilization strategies and knee instability.Methods. Twenty-one subjects with medial knee OA and genu varum and 19 control subjects were tested. Subjects stood with the test limb on a movable platform, comprising a plate that translated laterally to rapidly stress the knee's medial periarticular structures and create a potentially destabilizing sensation at the knee joint. Knee motion and muscle responses were recorded. Subjects rated the condition of their knee with a selfreport questionnaire about knee instability during daily activities.Results. Prior to plate movement, the OA subjects demonstrated more medial muscle co-contraction than did controls (P‫؍‬ 0.014). Following plate movement, the OA subjects shifted less weight off the test limb (P ‫؍‬ 0.013) and had greater medial co-contraction (P ‫؍‬ 0.037). OA subjects without knee instability had higher co-contraction of the vastus medialis medial hamstrings than did those who reported having instability that affected their daily activities (P ‫؍‬ 0.038). More knee stability correlated positively with higher co-contraction of the vastus medialis medial hamstrings prior to plate movement (r ‫؍‬ 0.459, P ‫؍‬ 0.042).Conclusion. Individuals with medial knee OA attempt to stabilize the knee with greater co-contraction of the medial muscle in response to laxity that appears on the medial side of the joint only. This strategy presumably contributes to higher joint compression and could exacerbate joint destruction, and therefore needs to be altered to slow or stop the progression of the OA disease process.

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Section: Discussionmentioning

confidence: 56%

Knee stabilization in patients with medial compartment knee osteoarthritis

Lewek¹,

Ramsey²,

Snyder‐Mackler³

et al. 2005

Arthritis & Rheumatism

111

View full text Add to dashboard Cite

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“…Peripheral adaptations in patients with ACLR might arise from surgery-related changes in sensory signals informing the brain on the onset of leg fall. Beside its mechanical role, the ACL is recognized as a major sensory structure, which contains receptors that have low thresholds to mechanical stimulation, and others that are activated only when the tension of the ligament is very high (Sjölander et al 2002;Solomonow 2006). Afferents emanating from joint mechanoreceptors have been shown to project to spinal motoneurons and interneurons, as well to a number of supraspinal structures (Sjölander et al 2002).…”

Section: Compensatory Postural Responses To Unpredictable Perturbationsmentioning

confidence: 99%

“…Beside its mechanical role, the ACL is recognized as a major sensory structure, which contains receptors that have low thresholds to mechanical stimulation, and others that are activated only when the tension of the ligament is very high (Sjölander et al 2002;Solomonow 2006). Afferents emanating from joint mechanoreceptors have been shown to project to spinal motoneurons and interneurons, as well to a number of supraspinal structures (Sjölander et al 2002). Overall, these findings would strongly suggest that mechanosensitive nerve endings of the ACL are involved in providing the CNS with information about the knee joint position and movement.…”

Section: Compensatory Postural Responses To Unpredictable Perturbationsmentioning

confidence: 99%

Early compensatory and anticipatory postural adjustments following anterior cruciate ligament reconstruction

et al. 2015

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“…Muscle spindles are considered to be the most important muscle mechanoreceptors for proprioception [35]. Their main functions are to record movements and positions, to be involved in muscle co-ordination and to regulate the nerve mediated muscle stiffness.…”

Section: Effects Of the The Sensorimotor Systemmentioning

confidence: 99%

“…Moreover, bradykinin injection into cervical facet joints [38] as well as the temporomandibular joint [39] was shown to affect the stretch sensitivity of the neck muscle spindles. Evidence suggests that the acuity of proprioceptive information from muscle spindle afferents can be impaired by fatigue, inflammation as well as trauma [35]. These items stimulate the chemoreceptors of the muscles [40], which via the gamma cells in the spinal medulla activate the gamma muscle spindle system.…”

Section: Effects Of the The Sensorimotor Systemmentioning

confidence: 99%