Sphenoid Sinus Metastasis Displacing the Cavernous Sinus

Ap, Vigliotti; Ja, Kenney; Kd, Dolan; Bc, Wen

doi:10.1177/000348949110000213

Cited by 2 publications

(1 citation statement)

References 10 publications

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“…Cellulae ethmoidales, Sinus frontalis 3. Nierenzellkarzinom Vigliotti et al [100] Sinus sphenoidalis Talgdrüsenkarzinom (Augenlid) Ii et al [101] Sinus maxillaris Adenokarzinom (Lunge) DeLara et al [102] Sinus sphenoidalis, Cellulae ethmoidales Karzinom der Cervix uteri Merimsky et al [103] Sinus sphenoidalis Karzinom der Tuba uterina Mochimatso et al [104] 1. Sinus frontalis 1.…”

Section: Mazerationsbefundunclassified

Die Metastasenabsiedlung in die Nasennebenhöhlen: Fallmitteilung und Literaturübersicht1

Prescher¹,

Brors²

2001

Laryngorhinootologie

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The case of an 87-year old man with widespread prostatic cancer is reported. During the autopsy macroscopically visible metastases were found within the frontal sinuses. These tumor masses destroyed the posterior osseous wall of the frontal sinus and formed polypoid bulging masses. In contrast to the macroscopically unaffected mucous membrane of the sphenoid sinus the maceration specimen of the skull base demonstrated a spongious-mossy, osteoplastic metastasis, lining the sphenoid sinus like a tapestry. This affection started from an exhaustive osteoplastic metastasis within the clivus. No metastases could be found in both antrums or the ethmoids. Retrospectively no symptoms from the paranasal sinuses could be eruated, only occasional pain of the frontal bone. The review of the world literature with 123 reports revealed 169 cases. Renal cell carcinomas most frequently metastasize into the paranasal sinuses (67 cases), followed by bronchogenic carcinomas (15 cases). Thyroid cancers and cancers of the mammary gland are responsible for 13 respectively 14 cases. The prostate also adds 12 cases. The paranasal sinuses are affected in diminishing frequency: maxillary sinus (55 cases), sphenoid sinus (37 cases), ethmoidal cells (23 cases) and frontal sinus (15 cases). In 38 cases exhaustive metastases affecting two or more paranasal sinuses are reported. The statement of literature, that metastases affecting the paranasal sinuses are much more frequent than reported, cannot be supported by our study, because the intensive autoptic investigation of 50 skulls of patients suffering from widespread cancers revealed no further cases of metastatic processes of the paranasal sinuses.

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Section: Mazerationsbefundunclassified

Die Metastasenabsiedlung in die Nasennebenhöhlen: Fallmitteilung und Literaturübersicht1

Prescher¹,

Brors²

2001

Laryngorhinootologie

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Factors in the Pathogenesis of Tumors of the Sphenoid and Maxillary Sinuses: A Comparative Study

Reino

2000

The Laryngoscope

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Objectives/Hypothesis To explain the processes that lead to the development of tumors in the maxillary and sphenoid sinuses. Study Design A 32‐year review of the world's literature on neoplasms of these two sinuses and a randomized case‐controlled study comparing the normal mucosal architecture of the maxillary to the sphenoid sinus. Methods Analysis of a 32‐year world literature review reporting series of cases of maxillary and sphenoid sinus tumors. Tumors were classified by histological type and separated into subgroups if an individual incidence rate was reported. Histomorphometry of normal maxillary and sphenoid sinus mucosa was performed in 14 randomly selected patients (10 sphenoid and 4 maxillary specimens). Specimens were fixed in 10% formalin, embedded in paraffin, and stained with periodic acid–Schiff (PAS) and hematoxylin. Histomorphometric analysis was performed with a Zeiss Axioscope light microscope (Carl Zeiss Inc., Thornwood, NY) mounted with a Hamamatsu (Hamamatsu Photonics, Tokyo, Japan) color‐chilled 3 charge coupled device digital camera. The images were captured on a 17‐inch Sony (Sony Corp., Tokyo, Japan) multiscan monitor and analyzed with a Samba 4000 Image Analysis Program (Samba Corp., Los Angeles, CA). Five random areas were selected from strips of epithelium removed from each sinus, and goblet and basal cell measurements were made at magnifications ×100 and ×400. Results The literature review revealed that the number and variety of tumors in the maxillary sinus are much greater than those in the sphenoid. The incidence of metastatic lesions to each sinus is approximately equal. No recognized pattern of spread from any particular organ system could be determined. On histomorphometric study there were no statistically significant differences between the sinuses in the concentration of goblet cells, basal cells, or seromucinous glands. Conclusions Factors involved in the pathogenesis of tumors of the maxillary and sphenoid sinuses include differences in nasal physiology, embryology, morphology, and topography. There are no significant histological differences in the epithelium and submucous glands between the two sinuses to explain the dissimilar formation of neoplasms.

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Sphenoid Sinus Metastasis Displacing the Cavernous Sinus

Cited by 2 publications

References 10 publications

Die Metastasenabsiedlung in die Nasennebenhöhlen: Fallmitteilung und Literaturübersicht1

Die Metastasenabsiedlung in die Nasennebenhöhlen: Fallmitteilung und Literaturübersicht1

Factors in the Pathogenesis of Tumors of the Sphenoid and Maxillary Sinuses: A Comparative Study

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