Spheno-Occipital Synchondrosis Fusion Correlates with Cervical Vertebrae Maturation

Abstract

The aim of this study was to determine the relationship between the closure stage of the spheno-occipital synchondrosis and the maturational stage of the cervical vertebrae (CVM) in growing and young adult subjects using cone beam computed tomography (CBCT). CBCT images with an extended field of view obtained from 315 participants (148 females and 167 males; mean age 15.6 ±7.3 years; range 6 to 23 years) were analyzed. The fusion status of the synchondrosis was determined using a five-stage scoring system; the vertebral maturational status was evaluated using a six-stage stratification (CVM method). Ordinal regression was used to study the ability of the synchondrosis stage to predict the vertebral maturation stage. Vertebrae and synchondrosis had a strong significant correlation (r = 0.89) that essential was similar for females (r = 0.88) and males (r = 0.89). CVM stage could be accurately predicted from synchondrosis stage by ordinal regression models. Prediction equations of the vertebral stage using synchondrosis stage, sex and biological age as predictors were developed. Thus this investigation demonstrated that the stage of spheno-occipital synchondrosis, as determined in CBCT images, is a reasonable indicator of growth maturation.

Three-dimensional assessment of the middle cranial fossa and central skull base following Herbst appliance treatment

“…The literature is consistent with the belief that growth of the spheno-occipital synchondrosis is associated strongly with the growth of the cranial base and that its full maturation occurs long after puberty. 14 In addition, rotational changes in the cranial base, as indicated by the deflection of the occipital bone relative to the anterior cranial base, may result from bone remodeling during pubertal growth. 15 As the evaluation of growth changes in the craniofacial complex is performed relative to reference structures, the measurements in this study were performed using the anterior cranial fossa as the structure of reference for superimposition based on the assumption proposed by Bjork 16 that the anterior cranial fossa is a stable reference during puberty.…”

Vestiges of Ossified Spheno-occipital Suture in an Elderly Patient With Down Syndrome and Lateral Skull Base Fracture

“…Down syndrome patients often have malformations of the cervical spine (29,32). SOS fusion correlates with maturation of the cervical vertebrae (33). So far it is unknown to what extent the development of the dorsal skull base correlates with the maturation of the cervical vertebrae of the Down syndrome patient (2,29).…”

Klasszikus és modern vizsgálómódszerek a csontérettségi kor és a pubertáskori növekedési csúcs meghatározására

“…CBCT-felvételeken nemcsak a csigolyák, hanem egyéb anatómiai képletek is segítségünkre lehetnek a csontérettség meghatározásában [33][34][35][36][37][38][39][40]. Bassed munkatársaival egy a craniofacialis régió növekedése szempontjából rendkívül fontos képletnek, a sphenooccipitalis synchondrosisnak a fúzióját tanulmányozta annak érdekében, hogy a kormeghatározásban igazságügyi orvosoknak segítséget nyújtson [36].…”

“…Fernández-Pérez munkacsoportja CBCT-felvételeken szoros kapcsolatot talált a csigolyaérettségi stádiumok és a synchondrosis fúziója között. Szignifikáns összefüggést találtak a synchondrosis 50%-os fuzionáltsági szintje és a pubertáskori növekedési csúcs között [37].…”