Spermatogenèse normale chez un homme avec défaut génétique de la LH

Meduri, Géri; Courtillot, Carine; Lahuna, Olivier; Kuttenn, Frédérique; Touraine, Philippe; Misrahi, Micheline

doi:10.1051/medsci/2010268-9690

Cited by 2 publications

(1 citation statement)

References 10 publications

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“…It is a gonadotropin hormone having an alpha subunit (the same as LH) and a specific beta subunit [30]. It controls spermatogenesis by acting on Sertoli cells [5].…”

Section: Fshmentioning

confidence: 99%

Hormonal Status Assessment of Infertile Congolese Men

Moukouma,

Poaty,

Diambalou

et al. 2024

ARSci

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Background: The pathologies causing male infertility are various (congenital or acquired) and concern several hormone-producing organs: the hypothalamus, pituitary gland, testes and adrenals. The hormonal dosage includes systematically testosterone, FSH and LH. These analyses often highlight hypogonadism hypogonadotropic or hypergonadotropic. They can sometimes be normal. The present study aimed to establish the hormonal profile of infertile men residing in Brazzaville. Patients and Methods: It was a crosssectional descriptive study during five years (from 2018 to 2023). It concerned 344 infertilemen with an abnormal spermogram and spermocytogram. The method was performed from the blood dosage of testosterone, FSH, and LH using the Elisa technique. Results: The hormonal assessment was not normal in 48.83% (168/344) of cases. Increased values of testosterone were noted in 6.10% of cases and decreased in 12.20%. Abnormal high values of FSH were observed in 14.24% of cases and decreased values in 8.13%. LH was elevated, i.e. 2.03% of cases and decreased in 6.10% of subjects. Conclusions: A hormonal disturbance was observed in almost half of the infertile men. It concerned the hypothalamus-pituitary and the testes axis and indicated mainly a state of hypogonadism with high FSH and low LH.

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“…It is a gonadotropin hormone having an alpha subunit (the same as LH) and a specific beta subunit [30]. It controls spermatogenesis by acting on Sertoli cells [5].…”

Section: Fshmentioning

confidence: 99%