Sperm Velocity in Seminal Plasma and the Association With Gender of Offspring

Balli, Kevin; Patton, William C.; Jacobson, John D.; Corselli, J.; King, Alan; Chan, Philip J.

doi:10.1080/01485010490250560

Cited by 6 publications

(12 citation statements)

References 20 publications

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“…16 Balli et al 16 found that faster sperm were associated with female offspring, contrary to our results in the present study, where we found that increased numbers of sisters were associated with slower sperm. However, we did not directly test for associations between offspring sex and sperm speed.…”

Section: Discussioncontrasting

confidence: 57%

“…Instead, we observed positive associations between the sex bias in the focal man's siblings and his sperm speed, suggesting a possible negative genetic correlation between the genes that make sperm fast or slow and the offspring gender. Neither the present study nor that of Balli et al 16 found any association between the proportion of sperm that swam with WHO (A1B) characteristics, and either sibling sex composition or offspring gender, respectively.…”

Section: Discussioncontrasting

confidence: 48%

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Sperm speed is associated with sex bias of siblings in a human population

Mossman

Slate²,

Birkhead³

et al. 2012

Asian J Androl

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Recent studies investigating possible causes of male subfertility have largely focused on how lifestyle or environmental factors impact on the process of spermatogenesis. Markedly, fewer studies have investigated those risk factors that result in reduced sperm quality, such as poor sperm motility. The speed at which sperm swim is a major predictor of fertility and is extremely variable in human populations. It has been hypothesized that offspring sex may be adaptively manipulated to maximize the offspring's reproductive fitness (e.g., parents with genes for good male fertility traits, such as high sperm speed, would produce primarily sons and fewer daughters because the offspring will inherit advantageous male fertility genes). Conversely, parents with poor male fertility genes would produce primarily daughters. We tested whether there was an association between how fast a man's sperm swam and the sex bias of his siblings in a sample of men attending clinic for fertility investigations with their partner and with a wide range of semen characteristics, including sperm speed. We found that the sex bias of a man's siblings is associated with his sperm speed; men with female-biased siblings had significantly slower sperm (judged using computer-assisted sperm analysis (CASA)) than men from male-biased sibships. This observation suggests family composition is an important factor that needs to be considered in future epidemiological and clinical studies of human fertility.

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Section: Discussioncontrasting

confidence: 57%

Section: Discussioncontrasting

confidence: 48%

Sperm speed is associated with sex bias of siblings in a human population

Mossman

Slate²,

Birkhead³

et al. 2012

Asian J Androl

View full text Add to dashboard Cite

show abstract

“…The present study expanded the original [1] 41 cases to the present 187 cases. Only cases with all male (N ¼ 96) or all female (N ¼ 91) offsprings were considered.…”

Section: Methodsmentioning

confidence: 97%

“…Studies that examine sperm parameters to indicate either a predominantly X-bearing or Y-bearing sperm population are lacking. A recent report showed an association of higher sperm velocity in seminal plasma from patients that conceived predominantly female offsprings when compared with patients with male offsprings after assisted reproductive technology (ART) treatment [1]. The null hypothesis was that there was no association between the offspring gender and sperm velocity in seminal plasma.…”

Section: Introductionmentioning

confidence: 97%

A Follow-Up Expanded Study of the Correlation of Sperm Velocity in Seminal Plasma and Offspring Gender

Maligaya

Chan²,

Jacobson³

et al. 2006

Archives of Andrology

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A preliminary study reported finding higher sperm velocity in seminal plasma in males of partners that conceived female offsprings. The null hypothesis was that sperm velocity was not related to the offspring gender. The objectives were: (a) to expand the previous study, and (b) to correlate offspring gender results with motility parameters determined through the computer-aided sperm analyzer (CASA) system. In combined fresh and frozen cycles (N = 187), sperm from cases with all female offsprings displayed higher curvilinear (48 +/- 1.0 mu/sec versus male 46 +/- 1.0, P < 0.05) and average path velocities (36 +/- 0.7 mu/sec versus male 34 +/- 0.7, P < 0.01). A criteria of less than 30 mu/sec or over 41 mu/sec average path velocity predicted 73 or 72% of the male or female offspring cases, respectively. A curvilinear velocity of less than 49 mu/sec or over 55 mu/sec predicted 58 or 59 % of the male or female offspring cases, respectively. Semen viscosity reflected in sperm velocity was linked to predominantly male or female sperm populations. Paracrine signals from the gender-skewed sperm precursor populations controlling viscosity merit further exploration.

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“…However, swim-up of human sperm for intervals ranging from 15 to 150 min failed to alter the ratio of X-to Y-bearing sperm [16]. Furthermore, analysis of live births after assisted reproductive procedures indicate that sperm from male patients that sired male offspring actually had slower curvilinear and average path velocities than patients siring female offspring [17] [18].…”

Section: Discussionmentioning

confidence: 99%

Variation among Beef Bulls in the Ratio of X- to Y-Chromosome Bearing Spermatozoa

Rorie¹,

Delgado²,

Lester³

2014

ARSci

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A study was conducted to evaluate variation in the ratio of X-to Y-bearing sperm of individual ejaculates and to determine any relationship between skewed sex ratio and either routine morphological evaluation or computer assisted sperm analysis (CASA). Semen was collected from bulls weekly for 6 consecutive weeks, sperm DNA was recovered and quantitative, and real-time PCR was used to determine the ratio of X-to Y-bearing sperm in each ejaculate. The overall mean of X-bearing sperm within ejaculates was 54.7% over the 6 weeks of semen collections. The percentages of X-bearing sperm were similar (P > 0.5) across all collections. Between bulls, there were differences (P < 0.05) in the mean percentage of X-bearing sperm. No significant correlations were found between CASA parameters and percentage of X-bearing sperm across bulls, so analysis was done within each bull. Different combinations of CASA and/or morphological parameters were found to correlate with the percentage of X-bearing sperm but the prediction equations were specific for individual bulls and unlikely to be of use across bulls. These results confirm that the ratio of X-to Y-bearing sperm may be skewed in some ejaculates of bull semen. Some sperm parameters measured by CASA or routine morphological evaluation were associated with semen sex ratio.

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Sperm Velocity in Seminal Plasma and the Association With Gender of Offspring

Cited by 6 publications

References 20 publications

Sperm speed is associated with sex bias of siblings in a human population

Sperm speed is associated with sex bias of siblings in a human population

A Follow-Up Expanded Study of the Correlation of Sperm Velocity in Seminal Plasma and Offspring Gender

Variation among Beef Bulls in the Ratio of X- to Y-Chromosome Bearing Spermatozoa

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