Sperm DNA fragmentation testing in clinical management of reproductive medicine
Ava Adler,
Bradley Roth,
Scott D. Lundy
et al.
Abstract:BackgroundApproximately 8%–12% of couples worldwide face infertility, with infertility of individuals assigned male at birth (AMAB) contributing to at least 50% of cases. Conventional semen analysis commonly used to detect sperm abnormalities is insufficient, as 30% of AMAB patients experiencing infertility show normal results in this test. From a genetic perspective, the assessment of sperm DNA fragmentation (SDF) is important as a parameter of sperm quality.MethodsIn this narrative study, we review and discu… Show more
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