Sperm Oxidative Stress and the Effect of an Oral Vitamin E and Selenium Supplement on Semen Quality in Infertile Men

Keskes-Ammar, L.; Feki-Chakroun, N.; Rebai, T.; Sahnoun, Zouheir; Ghozzi, H.; Hammami, Sami; Zghal, K.; Fki, H.; Damak, J.; Bahloul, Aymen

doi:10.1080/713828100

Cited by 63 publications

(53 citation statements)

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“…The serious drawback in this study, however, was that it lacked a double blind and placebo controlled method. Keskes-Ammar et al [88] did a similar study with randomization and control groups, and found overall improvements in sperm parameters. Vitamin C is a water-soluble antioxidant.…”

Section: Prescription Of Antioxidant Therapymentioning

confidence: 84%

What every gynecologist should know about male infertility: an update

Esteves¹,

Hamada

Kondray

et al. 2012

Arch Gynecol Obstet

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Extraordinary advances have been achieved in the field of male infertility over the past several years and many old concepts are now challenged. Therefore, it is imperative that male infertility physicians should update the gynecologists about the recent advances in the work-up of infertile men in terms of diagnosis and management. Such convention will help improve the standards of care for the infertile couple and enhance the cooperation between male and female reproductive endocrinologists.

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Section: Prescription Of Antioxidant Therapymentioning

confidence: 84%

What every gynecologist should know about male infertility: an update

Esteves¹,

Hamada

Kondray

et al. 2012

Arch Gynecol Obstet

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“…Therefore, PTX is a potent antioxidant, which reduces oxidative stress at cell level. Several antioxidant molecules, such as coenzyme Q10 [17], vitamin E [51], glutathione [52], and carnitine [53], have been proposed as therapeutic agents in infertile men with semen quality impairment. In our study, the beneficial effect of PTX on seminal plasma antioxidant capacity was documented with increased seminal plasma catalase-like and SOD-like activity.…”

Section: Discussionmentioning

confidence: 99%

“…These men frequently receive a number of medical therapies with doubtful efficacy [8]. The following medications have been used for male factor infertility: androgens [9], aromatase inhibitors [10], gonadotropins [11], antiestrogens [12], lycopene [13], a-tocopherol (Vitamin E) [14], glutathione [8], carnitine [15], selenium, N-acetyl-cysteine [16], coenzyme Q10 [17], and omega-3 [18]. Some of these medications have proven beneficial effects on sperm parameters.…”

Section: Introductionmentioning

confidence: 99%

Effect of pentoxifylline on semen parameters, reproductive hormones, and seminal plasma antioxidant capacity in men with idiopathic infertility: a randomized double-blind placebo-controlled study

Safarinejad¹

2010

Int Urol Nephrol

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“…41 Also, Keskes-ammar et al, 42 have reported benecial effects of vitamin E and selenium supplementation on human on semen quality.…”

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confidence: 99%

Protective effects of thornback ray muscle protein hydrolysate against dyslipidemia, oxidative stress and reduced fertility induced by high cholesterol diet in adult male rats

et al. 2018

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a Enzymatic thornback ray (Raja clavata) muscle hydrolysates have been shown to have antioxidant and antihypertensive activities in vitro. The Neutrase hydrolysate exhibited the highest activities, so it was investigated along with the undigested muscle to test their hypolipidemic, antioxidative and fertility effects in rats fed with a high-cholesterol diet (HCD). Animals were allocated into four groups of 5 rats each: a normal diet group (control), a HCD group, and two groups of HCD with a daily dose of undigested muscle (Und) or the hydrolysate (MH) at 0.7 g kg À1 of body weight. All animals received their respective treatments daily for 1 month. After the treatment period, serum lipid profiles, the activities of alanine aminotransferase and aspartate aminotransferase, the level of malonaldehyde, the activities of antioxidant enzymes (catalase and glutathione peroxidase) in the liver and sperm fertility parameters (in the epididymis and testis) were determined. Compared with those fed a standard diet, HCD induced dyslipidemia and oxidative stress, and decreased numerous reproductive parameters (mobility, count and viability). Interestingly, supplementing the HCD with thornback ray proteins attenuated all these anomalies, especially in the case where they were hydrolysed. These observations suggested that these proteins might contain bioactive peptides that possess hypocholesterolemic and antioxidant activities that ameliorate sperm damage.

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Sperm Oxidative Stress and the Effect of an Oral Vitamin E and Selenium Supplement on Semen Quality in Infertile Men

Cited by 63 publications

References 0 publications

What every gynecologist should know about male infertility: an update

What every gynecologist should know about male infertility: an update

Effect of pentoxifylline on semen parameters, reproductive hormones, and seminal plasma antioxidant capacity in men with idiopathic infertility: a randomized double-blind placebo-controlled study

Protective effects of thornback ray muscle protein hydrolysate against dyslipidemia, oxidative stress and reduced fertility induced by high cholesterol diet in adult male rats

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