Speeding Up the Healing of Burns with Honey

Postmes, Th. J.; Bosch, M.M.C.; Dutrieux, Richard P.; Baare, J. Van; Hoekstra, M.J.

doi:10.1007/978-1-4757-9371-0_6

Cited by 33 publications

(10 citation statements)

References 10 publications

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“…However, the stimulatory action of honey seems not to be due to sugar content alone, but is also due to other chemical constituents of honey. The present results are in agreement with that reported in vivo by Postmes (22), who found that the wound-healing ability of honey was superior to that of sugar.…”

Section: Discussionsupporting

confidence: 94%

The effect of Malaysian honey and its major components on the proliferation of cultured fibroblasts

Aljadi¹,

Enchang²,

Yusoff³

2014

Turk J Med Sci

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Background/aim: To examine, for the first time, the effect of a selected Malaysian honey and its major components on the proliferation of cultured fibroblasts. Materials and methods:Honey and some of its components, which include the sugars, the proteins, the hydrogen peroxide produced, and the phenolics, were exposed to cultured fibroblasts. The MTT colorimetric assay was used to assess cell viability and proliferation. Results:The stimulatory effect of honey on fibroblast proliferation was observed to be time-and dose-dependent. The continuous production of hydrogen peroxide by the honey-glucose oxidase system also acts to stimulate cell proliferation in a time-and dosedependent manner. The presence of phenolics with antioxidant properties, on the other hand, renders protection to the cells against the toxic effect of hydrogen peroxide. However, the presence of a growth factor-like substance in honey could not be ascertained. Conclusion:For the first time, honey and its major components were shown to exert stimulatory effects on cultured fibroblasts. Honey is therefore potentially useful in medicinal practices.

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Section: Discussionsupporting

confidence: 94%

The effect of Malaysian honey and its major components on the proliferation of cultured fibroblasts

Aljadi¹,

Enchang²,

Yusoff³

2014

Turk J Med Sci

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“…31,32 Frequent dressing changes might aid in the constant supply of hydrogen peroxide to the wound, which clinically translates into faster healing times witnessed in wounds treated with honey. 27,[33][34][35][36] In addition to its antimicrobial properties, honey can exert immunomodulatory action on different immune cells, and its components influence the formation of reactive oxygen species (ROS6) produced by these cells. Honey's anti-inflammatory actions can be explained by several mechanisms, including: 1) inhibition of the classical complement pathway; 2) inhibition of ROS formation; 3) inhibition of leukocyte infiltration; and 4) inhibition of cyclooxygenase-2 (COX-27) and inducible NO synthase expression.…”

Section: Discussionmentioning

confidence: 99%

A Case Report: Pilonidal Sinus Management with Medical-Grade Honey

Mr¹,

Rodrigues²

2019

Journal of the EWMA (JEWMA)

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“… 6 Honey has also been observed to attenuate the inflammatory phase of healing. 14 In addition, animal studies have documented improvement in epitheliazation. 15 …”

Section: Discussionmentioning

confidence: 99%

Objective and subjective scar aesthetics with topical Manuka honey post‐thyroidectomy: A randomized control study

Thamboo¹,

Mulholland²,

Matthews³

et al. 2016

World j. otorhinolaryngol.-head neck surg.

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ObjectiveLeptospermum Honey (Manuka honey) has proven to be effective in improving acute and chronic wound healing presumably due to its antibacterial and anti-inflammatory properties. The aim is to determine if Manuka honey decreases scar formation and results in a cosmetically appealing scar.MethodsA prospective single-blinded randomized control trial was performed. All patients received an 8 cm incision. Patients randomized to honey treatment were instructed to apply Manuka honey paste topically to the incision site once per day post surgery for 4 weeks. The patients' scar was then analyzed objectively by a blinded observer and subjectively at 4 and 8 weeks postoperatively. The primary outcome measure used was the Patient and Observer Scar Assessment Scale (POSAS).ResultsA total of 21 patients completed the entire scar analysis (honey treatment = 9, standard treatment = 12). There was no statistically significant difference between patient scar assessment scale and observer scar assessment scale at 4 and 8 weeks postoperatively.ConclusionDespite Leptospermum Honey's reported anti-inflammatory and antibacterial properties, this study did not show a difference in scar appearance when applied.

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Speeding Up the Healing of Burns with Honey

Cited by 33 publications

References 10 publications

The effect of Malaysian honey and its major components on the proliferation of cultured fibroblasts

The effect of Malaysian honey and its major components on the proliferation of cultured fibroblasts

A Case Report: Pilonidal Sinus Management with Medical-Grade Honey

Objective and subjective scar aesthetics with topical Manuka honey post‐thyroidectomy: A randomized control study

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