Speed and accuracy of a beam tracking system for treatment of moving targets with scanned ion beams

Saito, N.; Bert, Christoph; Chaudhri, Naved; Gemmel, Alexander; Schardt, D.; Durante, Marco; Rietzel, Eike

doi:10.1088/0031-9155/54/16/001

Cited by 65 publications

(91 citation statements)

References 36 publications

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“…For instance, a planned maximum range shift of ±10 mm in water equivalence (WE) leads to a resolution of 0.16 mm of WE for a typical configuration of the range shifter. Accuracy and its speed of the range shift depend on the specified range shift (approximately 1 mm WE deviation for 5 mm WE range shift in 10 ms), and it shows better accuracy for a slower scan speed (Saito, Bert, Chaudhri, Gemmel, Schardt, & Rietzel 2009b). The accuracy of the range adaptation is comparable to the uncertainties of CT data conversion to ion ranges (Jäkel et al 2001;Matsufuji et al 1998;Rietzel et al 2007).…”

Section: Longitudinal Trackingmentioning

confidence: 91%

“…The motion signal, dX, is sent via a motion sensor to the TCS to apply corresponding beam displacements dx, dy and dz selected from the LUT as it is performed in the corresponding patient case. During the irradiation the actual beam information (lateral position x, y, number of particles N and longitudinal displacement dz) and the motion signal dX are recorded in a time resolved manner (Saito, Bert, Chaudhri, Gemmel, Schardt, & Rietzel 2009b). As quality assurance phantom, a static water tank equipped with an array of 24 small ionization chambers (ICs) can be used as it had been performed for plan verification in therapy of static tumours at GSI (Karger et al 1999).…”

Section: Qa Measurementsmentioning

confidence: 99%

“…In this chapter at the section 2 we describe the beam tracking system and the pre-process to perform tracking. Technical detail concerning the speed and accuracy of the beam tracking system can be found in the report (Saito et al 2009b). In the section 2.1, as a pre-process of beam tracking, 4D treatment planning is described.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Scanned Ion Beam Therapy of Moving Targets with Beam Tracking

Saito¹,

Bert²

2012

Modern Practices in Radiation Therapy

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Section: Longitudinal Trackingmentioning

confidence: 91%

Section: Qa Measurementsmentioning

confidence: 99%

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Scanned Ion Beam Therapy of Moving Targets with Beam Tracking

Saito¹,

Bert²

2012

Modern Practices in Radiation Therapy

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“…Owing to the need to compensate for both CTV motion and the change in radiological path length in proton therapy, the German national heavy-ion physics laboratory, the Gesellschaft fü r Schwerionen, in Darmstadt, has established a method of using a motordriven compensation system for changes in radiological path length [46,47] and raster scanning [45,48].…”

Section: Beam Trackingmentioning

confidence: 99%

Treatment planning optimisation in proton therapy

McGowan¹,

Burnet²,

Lomax³

2013

BJR

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ABSTRACT. The goal of radiotherapy is to achieve uniform target coverage while sparing normal tissue. In proton therapy, the same sources of geometric uncertainty are present as in conventional radiotherapy. However, an important and fundamental difference in proton therapy is that protons have a finite range, highly dependent on the electron density of the material they are traversing, resulting in a steep dose gradient at the distal edge of the Bragg peak. Therefore, an accurate knowledge of the sources and magnitudes of the uncertainties affecting the proton range is essential for producing plans which are robust to these uncertainties. This review describes the current knowledge of the geometric uncertainties and discusses their impact on proton dose plans. The need for patient-specific validation is essential and in cases of complex intensity-modulated proton therapy plans the use of a planning target volume (PTV) may fail to ensure coverage of the target. In cases where a PTV cannot be used, other methods of quantifying plan quality have been investigated. A promising option is to incorporate uncertainties directly into the optimisation algorithm. A further development is the inclusion of robustness into a multicriteria optimisation framework, allowing a multi-objective Pareto optimisation function to balance robustness and conformity. The question remains as to whether adaptive therapy can become an integral part of a proton therapy, to allow re-optimisation during the course of a patient's treatment. The challenge of ensuring that plans are robust to range uncertainties in proton therapy remains, although these methods can provide practical solutions. The ability to create and deliver the ideal treatment plan, where the target volume receives 100% of the prescribed dose and normal tissue receives 0%, is the holy grail of radiation therapy [1]. It is, however, impossible to achieve this perfect balance. Instead, multiple trade-offs are required to achieve a clinically acceptable plan, so the problem becomes one of optimisation. There are many factors that can affect how ''optimised'' a patient's treatment can be. This review focuses on the challenges of proton therapy plan optimisation, particularly in regard to range uncertainties, and how to incorporate them into the plan evaluation and verification process.The nature of proton therapy makes the aim of cure without complications potentially more achievable, owing to the highly localised deposition of dose in the characteristic Bragg peak [2]. This relates predominantly to the ability to deliver high doses of radiation close to normal tissue structures, which would be dose limiting in conventional X-ray treatments, and to the finite range of protons, which results in a reduced integral dose to surrounding normal tissues.From a clinical perspective, the exact role of proton therapy has yet to be defined. However, for childhood cancers, proton therapy delivers a lower dose to tissues around the tumour than X-rays, resulting in less growth disturbance and l...

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“…The third strategy is adaptive pencil beam scanning, in which the pencil beam location/direction or even energy [59,73] is corrected by a signal from a motion detection system. This method is still in an early stage of development, however.…”

Section: Timing Considerationsmentioning

confidence: 99%

Beam Delivery Systems for Particle Radiation Therapy: Current Status and Recent Developments

Schippers

2009

Reviews of Accelerator Science and Technology

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An overview is given of different techniques of dose delivery applied in currently operating and planned particle therapy systems. Their advantages and disadvantages will be compared and consequences of the methods for the rest of the instrumentation will be discussed. The interrelationship between beam delivery at the patient and the accelerator system is shown by means of several concrete examples. Apart from a description of several subsystems in a particle therapy facility, design rules for optimizing the reliability of an accelerator and beam delivery system will be discussed, as well as some remarks concerning how to deal with future developments.

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Speed and accuracy of a beam tracking system for treatment of moving targets with scanned ion beams

Cited by 65 publications

References 36 publications

Scanned Ion Beam Therapy of Moving Targets with Beam Tracking

Scanned Ion Beam Therapy of Moving Targets with Beam Tracking

Treatment planning optimisation in proton therapy

Beam Delivery Systems for Particle Radiation Therapy: Current Status and Recent Developments

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