Speech Disorders in Right-Hemisphere Stroke

Dyukova, G. M.; Глозман, Ж.М.; Titova, E. Yu.; Kriushev, E. S.; Gamaleya, Anna A.

doi:10.1007/s11055-010-9301-9

Cited by 13 publications

(3 citation statements)

References 42 publications

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“…Our results are not consistent with this interpretation, as we found no evidence of an asymmetrical CBT in our group of adults. In contrast, our findings of highly variable functional lateralization for DDK are in agreement with other reports of acute dysarthria following right hemisphere infarcts (one case/six in Kim et al 2003;10% of patients in Urban et al 2006; less than a third in Kumral et al 2007; see Dyukova et al 2010 for a review). An early study by Urban and colleagues (Urban et al 1997) for instance had reported on 18 patients with mild to moderate dysarthria, six of whom had suffered a right hemisphere infarct.…”

Section: Discussionsupporting

confidence: 93%

Anatomy and lateralization of the human corticobulbar tracts: an fMRI-guided tractography study

et al. 2015

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The left hemisphere lateralization bias for language functions, such as syntactic processing and semantic retrieval, is well known. Although several theories and clinical data indicate a link between speech motor execution and language, the functional and structural brain lateralization for these functions has never been examined concomitantly in the same individuals. Here, we used functional MRI during rapid silent syllable repetition (/lalala/, /papapa/ and /pataka/, known as oral diadochokinesis or DDK) to map the cortical representation of the articulators in 17 healthy adults. In these same participants, functional lateralization for language production was assessed using the well-established verb generation task. We then used DDK-related fMRI activation clusters to guide tractography of the corticobulbar tract from diffusion-weighted MRI. Functional MRI revealed a wide inter-individual variability of hemispheric asymmetry patterns (left and right dominant, as well as bilateral) for DDK in the motor cortex, despite predominantly left hemisphere dominance for language-related activity in Broca's area. Tractography revealed no evidence for structural asymmetry (based on fractional anisotropy) within the corticobulbar tract. To our knowledge, this study is the first to reveal that motor brain activation for syllable repetition is unrelated to functional asymmetry for language production in adult humans. In addition, we found no evidence that the human corticobulbar tract is an asymmetric white matter pathway. We suggest that the predominance of dysarthria following left hemisphere infarct is probably a consequence of disrupted feedback or input from left hemisphere language and speech planning regions, rather than structural asymmetry of the corticobulbar tract itself.

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Section: Discussionsupporting

confidence: 93%

Anatomy and lateralization of the human corticobulbar tracts: an fMRI-guided tractography study

et al. 2015

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“…Disinhibited speech behaviors in, both deep and superficial lesions, display less precise specificity than the cortical structures. In analyzing published literatures on speech disorders of right hemispheric stroke in terms of locations, speech disorder types and possible mechanisms, poor understanding of mechanisms for the subcortical CA was pointed out and also that there is no single theory providing a complete explanation of the speech dysfunction in CA (17). …”

Section: Discussionmentioning

confidence: 99%

Neural Substrate Responsible for Crossed Aphasia

2013

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Crossed aphasia (CA) refers to language impairment secondary to right hemisphere lesion. Imaging analysis on the lesion location of CA has not yet been reported in the literature.This study was proposed to analyze the most prevalent lesion site related to CA. Brain MRI of 7 stroke patients satisfying the criteria for CA were used to define Region of interest (ROIs) before overlaying the images to visualize the most overlapped area. Talairach coordinates for the most overlapped areas were converted to corresponding anatomical regions. Anatomical lesions where more than 3 patients' images were overlapped were considered significant. The overlayed ROIs of 7 patients revealed the lentiform nucleus as the most frequently involved area, overlapping in 6 patients. Our study first demonstrates the areas involved in CA by lesion mapping using brain MRI, and lentiform nucleus is the responsible neural substrate for crossed aphasia.

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“…A stroke in the right cerebral hemisphere causes one or more types of language impairment (Dyukova, Glozman, Titova, Kriushev, & Gamaleya, 2010). Several studies have used various approaches to determine the role of the right hemisphere in language function.…”

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confidence: 99%

The Korean Version of the Right Hemisphere Language Battery: Adaptation and Reliability

Yun¹,

Chung²,

Kim³

et al. 2022

Commun Sci Disord

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Objectives: This study presents the Korean version of the Right Hemisphere Language Battery (K-RHLB), reports the preliminary results in healthy subjects, and evaluates inter- and intra-rater reliability. Methods: Fifty-two healthy patients underwent the RHLB, which was adapted to the Korean language. The rater reliability of the Emphatic Stress Test, which is a subtest of the battery, was examined. For inter-rater reliability, three raters evaluated the focus prosody of 35 randomly chosen subjects. For intra-rater reliability, one rater re-evaluated the prosody within 2-week and 3-month intervals. Results: The total mean score of the K-RHLB result was 110.75 ± 2.90 out of 116. The mean percentages of correct responses in the subtests were high and appeared in the following order: Discourse Analysis (99.9%), Written Metaphor Test (99.6%), Lexical Semantic Test (99.3%), Picture Metaphor Test (98.7%), Emphatic Stress Test (94.4%), Inference Test (83.5%), and Humor Test (76.5%). In addition, the inter-rater agreement was high (Gwet’s chance-corrected agreement coefficients AC1 of 0.83 ± 0.02, p < 0.001), as was the intra-rater consistency (Gwet’s AC1 0.93 ± 0.01, p < 0.001). However, some changes in evaluation criteria were confirmed for retest intervals longer than 2 months [Cochran’s Q (2) = 13.82, p < 0.001]. Conclusion: The preliminary results of the K-RHLB in healthy subjects showed overall high scores. Both inter- and intra-rater reliabilities were acceptable. The K-RHLB can be a starting point for more detailed assessment and elaborate intervention in patients with right hemisphere damage. The battery can also be used to evaluate neurodevelopmental disorders with symptoms such as deficits in understanding non-literal languages, semantic integration, and perception and production of appropriate prosody.

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Speech Disorders in Right-Hemisphere Stroke

Cited by 13 publications

References 42 publications

Anatomy and lateralization of the human corticobulbar tracts: an fMRI-guided tractography study

Anatomy and lateralization of the human corticobulbar tracts: an fMRI-guided tractography study

Neural Substrate Responsible for Crossed Aphasia

The Korean Version of the Right Hemisphere Language Battery: Adaptation and Reliability

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