Speech and language dysfunctions in patients with cerebrocortical disorders admitted in a neurosurgical unit

Abstract

Introduction: Speech and language abnormality among brain injury patients are common, especially during the acute stage. The details of same from Andhra Pradesh (AP) state are limited. The present study provides details of speech and language abnormality among brain damage patients, from a tertiary care hospital AP. Materials and Methods: This study was conducted at tertiary care hospital, Nellore, AP. Patients with acute brain damage due to traumatic brain injury (TBI), cerebrovascular accident (CVA), and postoperative cases of brain tumors were selected for the study. Detail of speech and language disturbances was accessed using Western Aphasia Battery. All patients were right-handed and Telugu was their first language. Results: There were totally 38 patients, of them 28 had TBI, 8 patients were postoperative cases of brain tumor, and 2 cases were of CVA. The mean age was 45.6 years. A total of 22 patients were literate. TBI patients with left cerebral hemisphere damage manifested with anomic, conduction, transcortical sensory, global, and Wernicke's aphasia. Four patients of postoperative brain tumor manifested with anomic and transcortical sensory aphasia had left-sided brain damage and mild dysarthria had right-sided brain damage patient. CVA patients had anomic aphasia and subcortical aphasia having right and left cerebral hemisphere damage, respectively. Conclusions: This study reports that acute brain damage due to various causes manifest with speech and language abnormality, especially when the left cerebral hemisphere is involved.

Hyperbaric oxygen therapy improves neurological function via the p38-MAPK/CCL2 signaling pathway following traumatic brain injury

“…Traumatic brain injury (TBI) is one of the great challenges to public health worldwide that presents various neurological impairments ranging from mild alterations of neurological function to an unrelenting comatose state and death [1,2]. Severe TBI easily resulted in permanent impairment that including cognitive impairments, mood disorders, sensory and motor changes, speech and language dysfunctions, and persistent vegetative state [3][4][5][6]. Major research and clinical efforts have focused on therapeutic interventions to secondary injuries following TBI, because of secondary injuries may persist for weeks to months.…”