Spectrum of pathogenic bacteria isolated from the bronchoalveolar lavage in a tertiary care centre at Hyderabad

Abstract

Pneumonia is the inflammation of the lung and several bacterial etiological agents are known to cause the infection. Studies have shown several gram negative bacteria including Pseudomonas spp, Klebsiella spp and gram positive bacteria such as Streptococcus spp are known to cause infection. In the present study we aim to evaluate the spectrum of bacterial isolates and their antibiotic sensitivity pattern isolated from BAL specimen. Materials and Methods: The retrospective study was carried out in a tertiary care center over a period of one year. The isolates were evaluated and identified with antibiotic sensitivity pattern. Results: The overall BAL specimen processed in a year were 90, in which culture were positive in 28 cases (31%). The organisms isolated were Pseudomonas aeruginosa, grown in 15 cases (52%), Klebsiella pneumoniae grown in 7 cases (28%), Escherichia.coli grown in 3 cases (10%) and Streptococcus pneumoniae in 3 cases (10%). Most of the organisms are sensitive to antibiotics. Conclusion:The present study has shown the most common isolate at our tertiary centre was Pseudomonas aeruginosa, followed by Klebsiella spp and in gram positive bacteria the common organism isolated was Streptococcus pneumoniae. Our results contribute to evaluate the common prevalent organisms causing pneumonia and also helps in improving the epidemiological knowledge.

Microbiota of Bronchoalveolar Lavage Samples from Patients of Lower Respiratory Tract Infection – A Changing Trend

“…LRTI affected predominantly middle-aged men in the present study (Mean age-43 yrs) which was comparable to study done in 2020 by Anisha et al 16 . This male predominance could be due to more outdoor activity, smoking, cultural conditions existing in our country.…”