Spectrum of hematological diseases diagnosed by bone marrow examination in a tertiary care hospital

Atchyuta, M.; Premalatha, Pidakala; Renuka, Inuganti Venkata; Krishnamashary, P. A. V; Tejeswini, Vaddatti

doi:10.18231/j.ijpo.2019.036

Cited by 4 publications

(7 citation statements)

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“…The number of male patients in the present study were 63% and the female patients were 37% with a male to female ratio of 1.7:1. This was in concordance with the studies done by Goyal, et al [5], Panigrahi, et al [6], Khan, et al [7], Atchyuta, et al [9], and Birare, et al [10].…”

Section: Resultssupporting

confidence: 92%

“…However, aspiration was dry tap in 4.17% cases whereas biopsy was cellular. The most common anaemia encountered was megaloblastic anaemia, which was comparable with the studies by Khatik, et al [4], Atchyuta, et al [9], Birare, et al [10], Bashir, et al [11], and Mehra, et al [12]. The second commonest anaemia encountered was aplastic anaemia, which was in concordance with the studies by Khatik, et al [4], Atchyuta, et al [9], and Mehra, et al [12].…”

Section: Resultssupporting

confidence: 89%

“…The basic panel markers 85 years, with the mean age being 50.22 years. The age distribution was comparable to the studies conducted by Panigrahi, et al [6], Khan, et al [7], Tyagi, et al [8] and Atchyuta, et al [9].…”

Section: Resultssupporting

confidence: 88%

“…The most common MPN encountered in the present study was Chronic Myeloid Leukaemia (CML) accounting for 62.5% of cases, followed by Polycythaemia Vera (PV) in 18.75% of cases, 6.25% cases each of Essential Thrombocythemia (ET), Myelofibrosis (MF) and Myeloproliferative Neoplasm-unclassified (MPN-U). In the studies conducted by Khatik, et al [4] and Atchyuta, et al [9], the most common disorder encountered was CML as in the present study.…”

Section: Resultssupporting

confidence: 59%

“…A total of 100 cases were studied. Among the 100 cases studied, 92% were haematological disorders et al [9], Birare, et al [10], and Vijaymohanan, et al [13] (Figure 1). The basic panel markers used in myeloma are CD19, CD56, CD38, CD138, CD81, CD27, CD45, cytoplasmic kappa and lambda.…”

Section: Resultsmentioning

confidence: 99%

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Study of Spectrum of Lesions in Bone Marrow Aspiration and Trephine Biopsy from a Tertiary Care Centre in South India

Gaurvi¹,

Teerthanath²

2022

Int J Pathol Clin Res

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Context: Bone marrow examination is an important diagnostic tool widely used in various haematological and non-haematological disorders. Bone marrow evaluation may either confirm clinically suspected disease or may provide the previously unsuspected diagnosis.Objectives: To study the spectrum of lesions, comparison and evaluation of diagnostic efficacy of the bone marrow aspiration and bone marrow biopsy findings in various haematological and non-haematological disorders.Design: A prospective study on 100 cases of bone marrow aspiration and biopsy was conducted between January 2019 to June 2020. Conclusion:This study concludes that bone marrow aspiration and biopsy are complementary to each other in diagnosing various haematological and non-haematological disorders. Therefore, simultaneous evaluation of both ensures accurate diagnosis, and further management.

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Section: Resultssupporting

confidence: 92%

Section: Resultssupporting

confidence: 89%

Section: Resultssupporting

confidence: 88%

Section: Resultssupporting

confidence: 59%

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Study of Spectrum of Lesions in Bone Marrow Aspiration and Trephine Biopsy from a Tertiary Care Centre in South India

Gaurvi¹,

Teerthanath²

2022

Int J Pathol Clin Res

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Utility of bone marrow aspiration and trephine biopsy in various haematological malignancies

Thakur

Thaker

et al. 2023

Int J Res Med Sci

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Background: The bone marrow examination is a useful and cost-effective diagnostic procedure in haematological practice for the diagnosis of haematological disorders. It may either confirm the clinically suspected disease or may provide the previously unsuspected diagnosis. The bone marrow examination can be done by bone marrow aspiration as well as by performing bone marrow biopsy. The aim of the study is to compare the diagnostic accuracy and rate of concordance between two modalities of bone marrow examination in diagnosis of haematological malignancies. Methods: The study was conducted at haematology section of the Department of Pathology, Government Medical College, Jammu spanned over a period of 2.5 years from June 2020 to December 2022. The clinical data along with physical examination, relevant haematological, biochemical and radiological investigations were also reviewed. After taking the informed consent bone marrow aspiration and bone marrow biopsy were done under aseptic precautions. Results: A total of 250 cases of haematological malignancies were studied over a 2.5 year period. The most common haematological malignancy was found to be leukemia 194 (77.6%) cases, followed by plasma cell dyscrasia with 30 (12%) cases, lymphomas and myeloproliferative disorders each with 11 (4.4%) cases and metastatic deposits 4 (1.6%) cases. In the present study, 64/250 (25.6%) patients underwent BMA and trephine biopsy simultaneously. A positive concordance was seen in 46 (71.8%) of the cases between the two methods and diagnostic discordance was observed in 10 (16.3%) of the cases. Conclusions: Bone marrow aspiration and biopsy both complement each other and should be evaluated simultaneously. This study emphasizes the need for greater vigilance in the early diagnosis and an interdisciplinary approach for the effective management of patients as well as inclusion of trephine biopsy as regular procedure for complete evaluation of patients with haematological malignancies.

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Spectrum of Hematological Disorders in Bone Marrow Examination

SANJANA,

CHERUKURI,

GARDAS

2024

Asian J Pharm Clin Res

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Objective: To study the bone marrow aspiration (BMA) trends and to observe and analyze the various patterns of hematological disorders in bone marrow examinations of patients attending a tertiary care teaching hospital. Methods: A 2-year study was done retrospectively in the department of pathology at the tertiary care teaching hospital. Relevant demographics, clinical details, intraprocedural details, and results were obtained through records and case files. Results: A total of 48 cases were studied. The most common diagnoses recorded were erythroid hyperplasia, nutritional anemia, megaloblastic anemia, acute leukemias, etc. Conclusion: Bone marrow cytology is a highly informative and diagnostic test procedure performed in evaluating blood and blood-related diseases. Some hematological conditions can be diagnosed with serological studies, and the need for an invasive test like BMA can be avoided.

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Spectrum of hematological diseases diagnosed by bone marrow examination in a tertiary care hospital

Cited by 4 publications

References 0 publications

Study of Spectrum of Lesions in Bone Marrow Aspiration and Trephine Biopsy from a Tertiary Care Centre in South India

Study of Spectrum of Lesions in Bone Marrow Aspiration and Trephine Biopsy from a Tertiary Care Centre in South India

Utility of bone marrow aspiration and trephine biopsy in various haematological malignancies

Spectrum of Hematological Disorders in Bone Marrow Examination

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