Spectrum of conjunctival tumors in an ocular oncology unit: review of 314 cases

Abstract

Purpose To report the frequency and spectrum of conjuctival tumors in an Ocular Oncology Unit from 1992 to 2008. Methods Retrospective noninterventional case series. Review of clinical charts of patients with the diagnosis of conjunctival tumor diagnosed at the Ocular Oncology Unit of the University Hospital of Valladolid from 1992 to june 2008. Demographic information and tumor features were introduced in Microsoft Access database. Results were analyzed with SPSS (version 15.0). Results Among a total of 314 cases, the mean patient age at diagnosis was 49 years, 43.3% were females and 56.7% males. Regarding the diagnosis, 149 cases (47.6%) were melanocytic, 124 (39.6%) epithelial, 30 (9.6%) soft tissues and 10 cases (3.2%) lymphoid origin. The majority of tumors were benign (63.9%) followed by the precancerous lesions (28.1%). Most of melanocytic lesions were benign (87.9%) and most epithelial were precancerous (64.5%). Conclusion Most frequent conjunctival tumors were melanocytic origin (the majority benign) and epithelial (the majority precancerous). Melanocytic, epithelial and lymphoyd tumors accounted for 90% of cases. These results are similar to others series previously published.

Tumores de la conjuntiva

“…Con respecto a los tumores melanocíticos, la mayoría son benignos, reconociéndose variaciones según la pigmentación racial y la edad de los pacientes. 1,2 En la unidad de Oncología Ocular del Hospital Clínico Universitario de Valladolid, entre 1993 y 2007 se han diagnosticado 314 tumores conjuntivales, de los cuales 149 (48%) fueron melanocíticos (87% benignos), 124 (39,6%) de origen epitelial (64,5% precancerosos), 30 (9,6%) originados en tejidos blandos y 10 (3,2%) de estirpe linfoid (3,4). En la mayoría de los casos, la diferenciación clínica entre lesiones benignas precancerosas y malignas es difícil, precisando la realización de una biopsia para el diagnóstico definitivo.…”