Spectrum of Congenital Anomalies among Surgical Patients at a Tertiary Care Centre over 4 Years

Agarwal, Arushi; Rattan, Kamal Nain; Dhiman, Ankur; Rattan, Ananta

doi:10.1155/2017/4174573

Cited by 6 publications

(10 citation statements)

References 8 publications

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“…16 However, unlike other studies, we found hydrocephalus as the most common anomaly, whereas others have reported NTDs as the most common anomaly of the CNS. [16][17][18] Different from Adeleye and Olowookere, 17 who reported most hydrocephalus being related to aqueductal stenosis, most of our cases of hydrocephalus were related to NTDs. Among NTDs, similar to other studies, we found spinal dysraphisms to be more common than encephaloceles.…”

Section: Discussioncontrasting

confidence: 99%

Pattern of congenital anomalies among pediatric surgical patients in a tertiary care hospital in northern Tanzania

Magwesela

Rabiel

Mung'ong'o

2022

World Jnl Ped Surgery

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BackgroundCongenital anomalies are major causes of morbidity and mortality in children under 5 years of age and make a significant contribution to the surgical burden of diseases. Most anomalies have multifactorial causes and commonly affect the central nervous, cardiovascular, gastrointestinal and musculoskeletal systems. Countries with improved pediatric surgical care have shown dramatic reductions in morbidity and mortality rates. The aim of this study was to analyze the pattern of congenital anomalies presenting in our surgical departments in patients under 5 years of age.MethodsA retrospective descriptive study was done. Data were obtained from clinical records of patients under 5 years of age, who underwent surgical correction of their congenital anomalies between 2017 and 2021. Analysis was done to identify the proportion of congenital anomalies managed in our setting.ResultsCongenital anomalies contributed 4.6% of overall surgical burden. Totally, 822 patients with congenital anomalies were included for analysis. The most commonly diagnosed congenital anomaly was inguinal hernia, followed by hydrocephalus, neural tube defects and cleft lips. The most commonly affected system was the central nervous system, anterior abdominal wall, orofacial and digestive system in decreasing order of frequency. Most of our patients presented outside the neonatal period (84.4%), and few (16.1%) had more than one system affected. Male children comprised 64%.ConclusionsDelayed presentation of children with congenital anomalies is still a significant problem in our area. Prevention through nutritional supplementation and antenatal screening is crucial. The true epidemiology of congenital anomalies in northern Tanzania is still obscure.

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Section: Discussioncontrasting

confidence: 99%

Pattern of congenital anomalies among pediatric surgical patients in a tertiary care hospital in northern Tanzania

Magwesela

Rabiel

Mung'ong'o

2022

World Jnl Ped Surgery

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“…It was found that CMGIT more commonly involved females (54.3%). This is contradictory to other studies where they found more prevalence of congenital anomalies in males 1,5 .…”

Section: Discussioncontrasting

confidence: 99%

“…And shamim et al has reported anorectal malformation as 20% of GIT malformations. In studies from India it has been reported as anorectal malformation as most common GIT anomaly making 20% of CMGIT 1,5,12 . In study by Ochaga et al has shown anorectal malformation as 66% of GIT anomalies 13 .…”

Section: Discussionmentioning

confidence: 99%

“…There is also variation in the prevalence in different regions of the world due to racial and social differences 1 . According to WHO statistics on causes of child death from 2000-2013, 276000 neonates die within first 4 weeks of life due to congenital anomalies worldwide 5,6 . According to figures from south east region, 8-15% deaths in perinatal period and 13-16% deaths in neonatal period are due to congenital anomalies 7,8 .…”

Section: Introductionmentioning

confidence: 99%

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Major Congenital Malformations of Gastrointestinal Tract Among Neonates Presenting to Tertiary Care

Sohrab¹,

Shabbir²,

Kousar³

et al. 2022

PJMHS

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Background: Major congenital malformations of gastrointestinal tract (CMGIT), are usually manifested in early neonatal period by signs of intestinal obstruction and may be life threatening. A broad spectrum of Gastrointestinal Tract (GIT) anomalies can be seen including both upper and lower GIT. As compared to other congenital anomalies, GIT anomalies are not well studied and till now very few studies have reported prevalence and pattern of GIT malformations. Objective: To determine different type of common gastrointestinal anomalies among neonates presenting at tertiary care hospital. Methods: This descriptive cross sectional study was done at National Institute of Child Health (NICH) Karachi over period of 6 months, from 1-8-17 to 31-1-18. All neonates presenting to emergency department and got hospitalized with CMGIT were enrolled. Results: There were 35 neonates enrolled with CMGIT. Out of these 16(45.7%) were male and 19(54.3%) were females. Mean age 9.4+3.82 (range 1-20) days. Mean weight was 2.5±0.98 (range 0.5-4.5) kg. Mean duration of symptoms was 5.8+1.72 (range 1-9) days. Among the CMGIT, 12 (34.3%) cases were of Anorectal malformation, persistent Vitelline duct was found in 6 (17.1%), Intestinal atresia in 4(11.4%), Intestinal stenosis in 5(14.3%), Hirshsprung disease in 4(11.4%) and Exomphalos in 4 (11.4%). Conclusion: Anorectal malformations were most common anomaly followed by persistent vitelline duct. Antenatal follow up and anomaly scan of all neonates should be done. Keywords: Gastrointestinal anomaly, Neonates, congenital anomaly.

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“…This is in congruence with other studies, such as that by Babu et al (45.94% in a 1000 birth cohort) and Agarwal et al (24.3%). 9 The proportion of women with fetal congenital malformations who had previous abortions was 9.27%. Almeida et al have shown that presence of previous abortions is a risk factor for congenital malformations.…”

Section: Discussionmentioning

confidence: 99%

Study of congenital fetal malformations among antenatal women in a tertiary care centre

Vaidya

Parelkar

et al. 2018

Int J Reprod Contracept Obstet Gynecol

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Background: Congenital malformations are morphological or functional anomalies that occur in the prenatal period as a result of genetic mutation, chromosomal abnormalities and adverse intrauterine environment. Early recognition is important. If congenital malformations are detected beyond the period of legal limit for medical termination of pregnancy, it carries immense burden on the pregnant woman.Methods: A descriptive observational study was conducted as a retrospective analysis of patient-records, over a span of 9 consecutive months in the Department of Obstetrics and Paediatric Surgery, at a tertiary care centre, Mumbai. The project was carried out to study demographic profiles, risk factors and system-wise distribution of pregnant women carrying malformed fetus.Results: The average annual incidence rate was 29 per 1000 deliveries. Of 151 patients, renal malformations were the commonest accounted for 40% of all congenital malformations. This was followed by central nervous system 32%, cardiovascular 14%, gastrointestinal 8% and musculoskeletal 3%. Congenital malformations were more common in multigravida than primigravida. 92% of congenital malformations were detected beyond 20 weeks of gestation. Previous abortions, hypothyroidism and raised sugars were associated high risk factors.Conclusions: The diagnosis of congenital malformation using ultrasonography occurs at a later gestational age than 20 weeks. For these patients a combined approach of the obstetrician/neonatologist/paediatric surgeon allows better counselling of parents and to permit preparation of the team to optimize neonatal outcomes.

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Spectrum of Congenital Anomalies among Surgical Patients at a Tertiary Care Centre over 4 Years

Cited by 6 publications

References 8 publications

Pattern of congenital anomalies among pediatric surgical patients in a tertiary care hospital in northern Tanzania

Pattern of congenital anomalies among pediatric surgical patients in a tertiary care hospital in northern Tanzania

Major Congenital Malformations of Gastrointestinal Tract Among Neonates Presenting to Tertiary Care

Study of congenital fetal malformations among antenatal women in a tertiary care centre

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