Spectroscopic study of orange G–β-cyclodextrin complex and its analytical application

Energetically favorable interactions between diclofenac sodium and cyclodextrin molecules in aqueous media

“…Thus, this structural difference gives rise to lower standard Gibbs energies for γ -cyclodextrin system as expected due to its larger cavity size. This behavior is similar to that observed for the β-CD:Orange G system [29]. …”

“…Similar enhancements were observed for the other cyclodextrin systems. It is known that the intensification of luminescent processes of a fluorescent guest molecule partially or totally encapsulated by the CD cavity is due to shielding from quenching and nonradioactive decay processes (decay of stable compounds under the influence of external stimuli such as heat or the presence of other molecular compounds in the vicinity) occurring in the bulk solvent [27][28][29]. Thus, the evidences observed demonstrate that the self-inclusion complex has been formed under this condition and DS was able to get into the CD cavity spontaneously in aqueous solution.…”

Investigation of inclusion complex of trazodone hydrochloride with hydroxypropyl-β-cyclodextrin

“…Their most popular feature is the marked difference of polarity between the internal and external surfaces: the inner part is made apolar by the glycosidic oxygens and methine protons, whereas the external surface is polar by virtue of the presence of secondary and primary hydroxyls on the large and small rims, respectively, (Atwood, Davies, Macnicol, & Vogtle, 1996;Khan, Forgo, Stine & D'Souza, 1998). The cyclodextrin structure provides a molecule shaped like a segment of a hollow cone which is capable of forming stable, supramolecular structures with various molecules (Hazekamp & Verpoorte, 2006;Jullian, Miranda, Zapata-Torres, Mendizabal, & Olea-Azar, 2007;Liu & Zhu, 2006;Rajabi, Tayyari, Salari, & Tayyari, 2008;Sagiraju & Jursic, 2008;Spamer, Muller, Wessels, & Venter, 2002;Wang, Han, & Feng, 2007;Yong & Zhu, 2006;Zhu, Sun, & Wu, 2007), fitting partially or completely in the host molecular cavity.…”

Infrared spectroscopy and Raman spectroscopy of cyclodextrin derivatives and their ferrocene inclusion complexes

“…During the last few years they have found a wide range of applications in food, pharmaceutical and chemical industries as well as agriculture and environmental engineering because of their nature as cavity molecules [1][2][3][4][5]. While all OH-groups of the CD molecules reach to the outside with the exterior showing hydrophilic characteristics, the cavity is hydrophobic.…”

“…IR spectroscopy is not very sensitive in investigating CD-adduct formation (see, for example, Refs. [2][3][4][5]), but using the corresponding Raman spectra, the inclusion compounds can be uniquely identified.…”