Spectroscopic Properties and Preparation of Some 2,3-Dimethoxybenzamide Derivatives

Crystal structure of 2,3-dimethoxy-N-(4-nitrophenyl)benzamide

“…In the IR spectrum, peaks corresponding to -C O-stretching and -NH-stretching indicate the presence of an amide linkage. These values are in agreement with those previously reported for similar compounds (Cakmak et al, 2016;Demir et al, 2015). et al, 1983) and two polymorphs (orthorhombic and monoclinic) of 4 0 -nitrosalicylanilide (respectively, KADZEU and KADZIY; Etter et al, 1988).…”

“…Benzamides and their derivatives are compounds of biological and pharmaceutical importance. A variety of benzamide derivatives have been synthesized by the interaction of aniline derivatives that carry electron-donating groups (anisidines, toluidines) and acyl chlorides (2,3-dimethoxybenzoyl chloride and 3-acetoxy-2-methylbenzoyl chloride) in a slightly basic medium (Cakmak et al, 2016;Demir et al, 2015).…”

“…The crude product was crystallized from acetonitrile (yield 2.09 g 63%; m.p. 448-451 K; Demir et al, 2015;Cakmak et al, 2016).…”

Crystal Structure of 3-Acetoxy-2-methyl-<i>N</i>-(4-nitrophenyl)benzamide

“…They are also widely used in the industrial and agricultural sectors. 2 For this reason, studies concerning the preparation of new amide compounds continue to have increasing populatiry. 3 In previous work, we synthesized many substituted secondary amide compounds such as 2,3-dimethoxybenzoic acid and aniline derivatives.…”

“…The molecular structures of synthesized compounds have also been determinated by an x-ray diffraction method. [1][2][3][4] In this research 3-acetoxy-2-methyl-N-(4-nitrophenyl)benzamide ( Fig. 1) was prepared using a solution of 3-acetoxy-2-methylbenzoyl chloride (10 mmol) in THF (5 mL), which was added dropwise to a solution of 4-nitroaniline (10 mmol) and triethylamine (10 mmol) in THF (5 mL) at room temperature.…”