Spectroscopic Measurements in Patients with Completely Ruptured Anterior Cruciate Ligament before and after RegentK and Physiotherapy

Abstract

Background: The goal of this study was to investigate acute effects of a special kind of manual therapy developed by Mohamed Khalifa (RegentK) compared to standard physiotherapy on regional oxygen saturation (rSO₂) of knee tissues in patients with completely ruptured anterior cruciate ligament (ACL). Methods: Twenty patients were enrolled in this study and randomly assigned to receive either RegentK (group A; n = 10, 8 female, 2 male, mean age ± SD 31.3 ± 8.5 years) or physiotherapy (group B; n = 10, 6 female, 4 male, mean age 34.8 ± 10.2 years). The values of rSO₂, assessed using near-infrared spectroscopy, were registered anterolaterally and anteromedially on both the injured and the healthy (control) knee. Results: rSO₂ increased significantly (p < 0.001) after RegentK on both registration sites of the injured knee, whereas after physiotherapy only the anterolateral side showed significant increases. Interestingly, we found significant increases in rSO₂ also on the control knee after RegentK; in group B, these results were insignificant. Conclusion: We conclude that manual therapy influences the hemodynamics of muscles and deeper structures. The results will also serve to quantify the effects of nonpharmacological and nonsurgical interventions (e.g. RegentK) on the microvascular circulation in deep tissue after a complete rupture of the ACL.

RegentK: The Scientific Investigation of a 40-Year-Old Method in Regenerative Medicine

“…Based on this study, we concluded that manual therapy influences the hemodynamics of muscles and deeper structures. The results also serve to quantify the effects of non-pharmacological and non-surgical interventions on the microvascular circulation in deep tissue after a complete rupture of the ACL [6]. …”

“…Note the higher temperature in the injured knee compared to the control knee before treatment, whereas the temperature of the foot on the injured leg is initially lower than the temperature of the foot on the healthy leg (compare the colour of the toes). Modified from Litscher et al [6]. …”

Innovative Integrative Medicine

“…Apart from those mentioned by Pan and Zhou [4], new technical applications in manual therapy have to be mentioned here; further details on this topic can be found in an original paper published this year in this journal, too [5]. …”