Spectroscopic investigations of pentobarbital interaction with human serum albumin

Human serum albumin binding and cytotoxicity studies of surfactant–cobalt(III) complex containing 1,10-phenanthroline ligand

“…Interaction with albumin is also of importance to understand the drug toxicity and its distribution in the organism. It has been an interesting research field in life science, chemistry and clinical medicine [1][2][3].…”

Interaction of Retinol with HSA using Spectroscopic Techniques

“…Human serum albumin (HAS) is the most abundant protein in blood plasma and is able to bind and thereby transport various compounds such as fatty acids, hormones, bilirubin, tryptophan, steroids, metal ions, therapeutic agents and a large number of drugs . HSA serves as the major soluble protein constituent of the circulatory system, it contributes to colloid osmotic blood pressure, it can bind and carry drugs which are poorly soluble in water (Abu Teir et al, 2010). HSA concentration in humanplasma is 40 mg/ml (Tusharet al 2008).…”

Combined molecular docking and multi-spectroscopic investigation on the interaction between Eosin B and human serum albumin

“…Nowadays, many studies on the binding of drugs to HSA have been carried out [7][8][9][10][11][12], but only few results have been published on the interaction between dyes and HSA [13][14][15]. There is an evidence of conformational changes of albumin induced by its interaction with dyes and other ligands [11][12][13][14][15].…”

“…There is an evidence of conformational changes of albumin induced by its interaction with dyes and other ligands [11][12][13][14][15]. The widespread commercial use of dyes today also makes it necessary to study structural dynamics of dye-protein complexes for understanding the biological effects and functions of dyes in body.…”