Spectroscopic differentiation and chromatographic separation of regioisomeric indole aldehydes: Synthetic cannabinoids precursors

Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) Copolymer 2D Single Network at the Air–Water Interface

“…In addition, the aromatic CC band of the benzene is observed at 1594 cm –1 . A doublet at 2870 and 2745 cm –1 is characteristic of the aldehyde C–H vibration . Finally, the aromatic sp 2 C–H band is detected as a doublet in the 3020–3070 cm –1 IR frequency range …”

“…A doublet at 2870 and 2745 cm −1 is characteristic of the aldehyde C−H vibration. 42 Finally, the aromatic sp 2 C−H band is detected as a doublet in the 3020−3070 cm −1 IR frequency range. 42 Table S1 summarizes these main chemical bonds from the recorded ATR−FTIR spectra.…”

“…42 Finally, the aromatic sp 2 C−H band is detected as a doublet in the 3020−3070 cm −1 IR frequency range. 42 Table S1 summarizes these main chemical bonds from the recorded ATR−FTIR spectra.…”

Fast & fluorinated – Development and validation of a rapid benchtop NMR approach and other routine screening methods for the detection and quantification of synthesized fluorofentanyl derivatives

“…These compounds tend to exhibit similar chemical and chromatographic properties, and their mass spectra are often equivalent. This complicates the identification of specific drug regioisomers, hence the requirement for specific analytical methods to identify regioisomers of synthetic cannabinoids, [22][23][24][25] fluoroamphetamines, [26] chloroamphetamines, [27] cathinones, [28] etc. Identification of drug regioisomers may also require the use of multivariate analysis in conjunction with mass spectral data.…”

Gas Chromatography—Fourier Transform Infrared Spectroscopy for Unambiguous Determination of Illicit Drugs: A Proof of Concept

“…In some circumstances, positional isomers, and diastereomers may be separated chromatographically, but identification cannot be attained, univocally, on the sole basis of the retention behavior. Whenever structural assignment is mandatory, a further analytical step may be required, consisting of compound isolation or targeted organic synthesis (followed by purification/concentration, eventually) prior to further characterization (Abiedalla et al, 2019 ; Kraenenburg et al, 2019 ).…”