Spectroscopic characterization of Cu(II), Ni(II), Co(II) complexes, and nano copper complex bearing a new S, O, N-donor chelating ligand. 3D modeling studies, antimicrobial, antitumor, and catalytic activities

Metal complexes of hydrazone–oxime derivative as promising in vitro antimicrobial agents against some fungal and bacterial strains

“…They have shown considerable antimalarial, 1 anti-insecticidal, 2 anticancer, 3 anticholinesterase, 4 antitumor, 5,6 anti-tuberculosis, 7 antifungal, [8][9][10][11] antibacterial, 8-11 antihyperglycemic, 12,13 anti-infective, 14 antiradical, 15 antioxidant, [16][17][18] antimicrobial, 19,20 antitrypanosome, 21 antidiabetic, anti-inflammatory, 22,23 antiviral, [23][24][25] antidepressant and nootropic, 26 and gastroprotective activities. 27 Furthermore, They act as enzyme inhibitors, 23,[28][29][30] catalysts in various reactions, [31][32][33] and excellent anticorrosion to protect the metals and alloys as steel. 34 Also they can serve as a solid source precursor for metal oxide nanoparticles.…”

Centro‐symmetric copper complex as a novel antitumor drug for therapeutic applications: Fabrication, structure, theoretical calculations, cytotoxicity, DNA binding/cleavage, and molecular docking

“…The broad absorption band in the visible region (639 nm) is attributed to 2 B 1g 2 Eg. [51][52] Furthermore, the calculated magnetic moment of Cu(AHC) 2 (1.68 B.M.) agreed with the value of the square planner geometry.…”

“…A square planner geometry for the Cu(AHC) 2 complex was indicated by the profile of the ESR spectrum with the calculated g values. [51,55] Calculated values for g jj and g ┴ are 2.10 and 2.07, respectively, and g av value (g av = 1 / 3 (g + 2 g ⊥ )) is equal to 2.08. [56] The higher value of g jj compared with g ⊥ indicates that the unpaired electron is predominantly in the dx 2 -y 2 orbital, giving 2 B 1g as the ground state.…”

Monometallic complexes of novel dihydrazone‐oxime ligand: Synthesis, structure, spectral, DFT, and in vitro bioactivity investigation against fungal, bacterial, and tumor cells

“…[27] Furthermore, these compounds also have the potential to be an excellent candidate for oral medicines, such as their use to treat genetic illnesses like thalassemia. [28] They have enzymatic inhibition effect, [22,[29][30][31] catalytic activity in different mechanism, [32][33][34] and well anti-corrosion to safeguard the alloy and metal. [35] It can also be used as a precursors for nano-sized metal oxide.…”