Abstract:A simple, rapid and sensitive spectrophotometric method for determination of sulphadiazine (SDZ) in aqueous solution is described. The method iis based on the oxidation of SDZ by potasium Periodate, and coupling with ortho-amino phenol to give a violet colour of maximum absorbaance at 532 nm. Beer's law is obeyed over the concentration range of 5-40 µg /ml of SDZ with a (R2=0.9980) and molar absorptivity 5581.6 L.mol-1.cm-1 and a relative error in the range of - 0.06 - 2.3 % and a relative standard deviatio… Show more
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