Spectrophotometric Determination of Amlodipine Besylate in Pure Forms and Tablets

A critical study on the application of the zero-crossing derivative spectrophotometry to the photodegradation monitoring of lacidipine

“…LAC is an antihypertensive drug with dihydropyridine structure, acting by blocking L-type calcium channels. LAC is extremely sensitive to light, similarly to all other drugs belonging to the same chemical class [9][10][11][12][13][14][15]. The detailed photo-chemical degradation process of the drug has recently been reported in the literature [16].…”

Stability indicating RP-HPLC method for simultaneous determination of amlodipine and benazepril hydrochloride from their combination drug product

“…Detailed survey of literature for AM revealed several methods based on different techniques, viz. HPLC [6][7][8][9][10][11][12][13], HPTLC [14][15][16], OPLC [17], SFC [18], UV spectrophotometry [19][20][21][22][23][24][25][26][27][28][29][30][31], and MEKC [32] for its determination from pharmaceuticals. Similarly, survey of literature for BH revealed methods based on HPLC [33][34][35][36][37][38][39][40], HPTLC [41], UV spectrophotometry [42][43][44][45][46][47], eletroanalytical techniques [48,49], and CE [50][51][52] for its determination from pharmaceuticals.…”

Development and Application of Rp-Hplc Method for Dissolution Study of Oral Formulations Containing Amlodipine Besylate

“…GC method was also proposed following trimethylacetyl derivatization in human plasma as matrix using ECD [15]. GC-MS, HPLC, spectroscopic methods are also reported for drug substance and AMB pharmaceutical formulation (tablets) [16][17][18][19][20][21][22]. Films for oral drug delivery most recently were made official in the European Pharmacopoeia, edition 7.4 and subordinated to the monograph 'oromucosal preparations' [23].…”