Spectral, Magnetic and Biological Studies of Mechanochemical Synthesis of Metal (Ii) Complexes Derived From Ciprofloxacin

Abstract

The mechanically synthesized complexes of ciprofloxacin were characterized by physical methods, spectral and biological studies. Spectral studies show that; in the complexes, the ciprofloxacin acted as bidentate ligand which coordinated to the metal ion through the ring carbonyl oxygen and one of the Oxygen atoms of the carboxylate group. Results from microanalysis data shows 1:2 metals to ligand ratio. All the complexes show strong antibacterial activity at all concentrations compared with the free ligand (ciprofloxacin).